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Description
Glycine Zinc Salt Monohydrate is the zinc salt of glycine, the simplest amino acid, supplied in monohydrate form and prepared specifically for protein research applications. The compound brings together two components that are individually important in biochemistry: glycine, which serves both as a protein-building amino acid and as a buffering agent, and the zinc ion, a metal cofactor involved in hundreds of enzymes and structural proteins. In the laboratory, this material functions as a readily soluble source of coordinated zinc that is comparatively gentle toward proteins, making it appropriate for experiments that require the addition of zinc ions without disturbing the stability of the macromolecules under study.
The property that makes this material a preferred choice is its nature as an amino acid–metal complex, which delivers zinc ions in a more controlled chemical environment than a simple inorganic salt provides. Coordination by glycine helps keep the zinc ion in solution and reduces its tendency to precipitate as the hydroxide at near-neutral pH, a problem that frequently interferes with protein experiments. The "for Protein Research" designation indicates that the material has been prepared to a quality level intended for biochemical applications that are sensitive to the condition of the reagent used.
In Indonesian laboratories, this reagent is typically encountered in university biochemistry and molecular biology groups, in research institute laboratories working on enzymes and protein structure, and in analytical settings where a defined zinc source is needed for buffer and assay preparation. It is generally used in small, carefully weighed quantities as part of a larger experimental workflow rather than as a bulk consumable, which is why it is usually held as a stock item in a shared reagent store.
Laboratory Applications
- Protein research and protein characterization studies, where a soluble, protein-compatible zinc source is needed to supply the metal ion without introducing the harsher chemical conditions associated with simple inorganic zinc salts.
- Enzyme studies involving zinc-dependent enzymes, since many enzymes require zinc as a cofactor and this coordinated form allows the ion to be introduced into assay mixtures in a controlled manner.
- Preparation of buffers and reaction media requiring defined zinc content, taking advantage of the fact that glycine coordination helps maintain zinc solubility at pH values close to neutral.
- Reconstitution or supplementation experiments on metalloproteins, where zinc must be added back to a protein preparation under conditions that preserve the stability of the macromolecule being examined.
- Teaching and method development work in biochemistry, where a well-characterized amino acid–metal complex illustrates metal coordination chemistry while remaining suitable for use in genuine protein experiments.
Specifications
- Brand: TCI, catalogue number G0215
- CAS number: 14281-83-5
- Category: Life Science > Biochemicals and Reagents > Amino Acids
- Grade designation: for Protein Research
- Chemical form: zinc salt of glycine, supplied as the monohydrate
- Pack sizes: available in standard TCI research pack sizes; please confirm the required size when ordering
- Storage: store in a cool, dry place in the original tightly closed container
Handling and Storage
Store the container in a cool, dry location away from direct sunlight, moisture, and sources of heat, and keep it tightly closed when not in use, since the monohydrate form can take up or lose water if left exposed to ambient laboratory air. The original manufacturer's container is the most suitable storage vessel; if transfer is necessary, use a clean, dry, chemically compatible bottle with a secure closure and label it clearly with the compound name and CAS number. Weigh the material using clean, dry spatulas to avoid contaminating the bulk stock, and prepare solutions with water or buffer of a quality appropriate to the intended protein work. General laboratory precautions apply: wear safety glasses, a laboratory coat, and suitable gloves, avoid generating dust during weighing, work in a well-ventilated area or fume hood, and wash hands thoroughly after handling. Consult the manufacturer's safety data sheet before first use and dispose of residues according to local chemical waste regulations.
![14281-83-5 Glycine Zinc Salt Monohydrate [for Protein Research] (CAS 16800-66-1) - TCI G0215 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510G0215.jpg?v=1769180861&width=1946)
![14281-83-5 Glycine Zinc Salt Monohydrate [for Protein Research] (CAS 16800-66-1) - TCI G0215 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510G0215.jpg?v=1769180861&width=1445)
