3-[[2-(Methacryloyloxy)ethyl]dimethylammonio]propane-1-sulfonate TCI M1971

Chemical Identity

CAS No.: 3637-26-1
Formula: C11H21NO5S
Molecular weight: 279.36 g/mol
Purity: >98.0%(T)(N)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 3-[dimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azaniumyl]propane-1-sulfonate
SMILES: CC(=C)C(=O)OCC[N+](C)(C)CCCS(=O)(=O)[O-]
InChIKey: BCAIDFOKQCVACE-UHFFFAOYSA-N
PubChem: CID 3034140

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TCI M1971 3-[[2-(Methacryloyloxy)ethyl]dimethylammonio]propane-1-sulfonate is a zwitterionic monomer belonging to the sulfobetaine methacrylate family. Within a single molecule it carries both a positively charged ammonium group and a negatively charged sulfonate group, together with a polymerizable methacrylate group. In materials science and polymer chemistry laboratories, this monomer serves as a key building block for constructing polymers that are strongly hydrophilic while remaining overall electrically neutral. The paired-charge combination gives the resulting polymers a distinctive surface character that is widely sought in the development of materials intended to contact aqueous media and biological systems.

The principal characteristic that makes this monomer a preferred choice is the ability of its zwitterionic group to bind water molecules very strongly, so that the polymer layer formed tends to resist the attachment of proteins and microorganisms. This property forms the basis for developing antifouling coatings and surfaces that are compatible with biological systems. The methacrylate group can be polymerized through free-radical routes, including controlled polymerization techniques, allowing researchers to assemble homopolymers, block copolymers, or hydrogel networks with an architecture suited to the intended study.

In Indonesian laboratories, this monomer is typically used in university research groups and institutional laboratories working on polymer synthesis, surface modification, and biomaterials development. It is generally handled at bench scale for the preparation of polymer solutions, coating formulations, and hydrogel systems, where the same material supports both exploratory synthesis work and the more systematic characterization studies that follow.

Antifouling coating development: the strong water-binding character of the zwitterionic group produces surfaces that resist protein adsorption and microbial attachment, which is the central requirement in this work.
Biocompatible surface modification: grafting polymers derived from this monomer onto substrates yields hydrophilic, charge-balanced interfaces that behave gently toward biological systems in contact with them.
Hydrogel network synthesis: the polymerizable methacrylate group allows the monomer to be incorporated into crosslinked networks that retain large amounts of water while remaining overall neutral.
Block copolymer preparation via controlled polymerization: the methacrylate functionality is compatible with controlled radical techniques, giving researchers defined architectures with zwitterionic segments placed where intended.
Fundamental studies of polyzwitterion behaviour: the paired ammonium and sulfonate charges make this a reference monomer for investigating how zwitterionic polymers interact with water and dissolved ions.

Brand	TCI
CAS number	3637-26-1
Molecular formula	—
Purity	—
Category	Materials Science > Polymer/Macromolecule Reagents > Monomers
Pack sizes	available in standard laboratory research pack sizes; please confirm the currently offered packaging when ordering
Physical form	supplied as a solid reagent-grade chemical for laboratory research use
Storage	store in a tightly closed original container in a cool, dry place away from moisture, following the manufacturer's instructions on the product label

Store the container tightly closed in a cool, dry, well-ventilated area, away from direct sunlight, heat sources, and ignition sources. Because this is a polymerizable monomer, avoid prolonged exposure to elevated temperatures. Keep the material in its original supplier container, or in a clean, chemically compatible and clearly labelled container if transferred. Handle inside a fume hood using laboratory gloves, safety glasses, and a laboratory coat, and avoid contact with skin and eyes as well as inhalation of dust. Weigh and transfer with clean, dry equipment to prevent moisture ingress and contamination, close the container promptly after use, and always consult the manufacturer's Safety Data Sheet before handling and disposal.

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