3-[[2-(Methacryloyloxy)ethyl]dimethylammonio]propionate TCI M2359

TCI M2359 3-[[2-(Methacryloyloxy)ethyl]dimethylammonio]propionate is a zwitterionic monomer of the carboxybetaine class that carries a methacrylate group as its polymerizable moiety. It is classified within pharmaceutical development reagents, specifically under drug delivery systems (DDS). In the laboratory, monomers of this type are used to prepare polymers and hydrogels whose surfaces are strongly hydrophilic, enabling the resulting materials to resist non-specific adsorption of proteins and attachment of cells on the surfaces that researchers are developing.

The property that makes this monomer stand out is its zwitterionic structure, namely the presence of a positively charged quaternary ammonium group and a negatively charged carboxylate group within the same molecule. This combination produces a strong hydration layer around the polymer chain and forms the basis of the antifouling behaviour sought in biomedical materials. Its methacrylate group permits free-radical polymerization, including controlled polymerization techniques, so researchers can assemble homopolymers as well as copolymers with chain lengths and compositions adjusted to the requirements of a given material design.

In Indonesia, this monomer is typically found in polymer research laboratories, pharmaceutics laboratories, and university and institutional research groups working on biomaterials and drug delivery. It is normally handled as a specialty research reagent rather than a routine bulk chemical, obtained in the pack size that matches a planned series of polymerization experiments, and used alongside initiators, comonomers, and solvents already established in the laboratory's synthetic workflow.

• Antifouling surface coatings: the zwitterionic carboxybetaine structure builds a strong hydration layer that limits non-specific protein adsorption on material surfaces under development.
• Zwitterionic hydrogel preparation: the methacrylate group allows free-radical crosslinking into highly hydrophilic hydrogel networks suitable for biomaterials and drug delivery research studies.
• Drug delivery carrier synthesis: as a DDS-category reagent, it is incorporated into polymer carriers whose surfaces must resist non-specific biological interactions during formulation work.
• Controlled polymerization studies: compatibility with controlled radical polymerization techniques lets researchers target defined chain lengths and narrow, reproducible polymer architectures for systematic experiments.
• Functional copolymer design: it can be copolymerized with other methacrylate monomers so that composition and zwitterionic content are tuned to the intended material property profile.

• Product code: M2359

Store the material in its original tightly closed container, following the storage temperature and conditions stated on the manufacturer's label and safety data sheet. Keep the container well sealed to limit exposure to moisture and air, and protect it from heat and direct sunlight. As a polymerizable methacrylate monomer, it should be kept away from heat sources and conditions that could promote unintended polymerization. Handle the reagent in a fume hood or a well-ventilated area, wear gloves, safety goggles, and a laboratory coat, and avoid contact with skin and eyes. Use clean, dry glassware or spatulas when weighing to prevent contamination of the stock, and dispose of residues in accordance with the laboratory's chemical waste procedures.

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