2-[[2-(Methacryloyloxy)ethyl]dimethylammonio]acetate TCI M3185

Chemical Identity

CAS No.: 62723-61-9
PubChem: CID 11806082·SID 468592322
Formula: C10H17NO4
Molecular weight: 215.25 g/mol
Purity: >98.0%(HPLC)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 2-[dimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azaniumyl]acetate
SMILES: CC(=C)C(=O)OCC[N+](C)(C)CC(=O)[O-]
InChIKey: UZMZRFVLRULBOV-UHFFFAOYSA-N

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2-[[2-(Methacryloyloxy)ethyl]dimethylammonio]acetate with CAS number 62723-61-9 is a zwitterionic monomer from TCI belonging to the carboxybetaine methacrylate family. The molecule carries a methacrylate group that can be polymerized through free radical pathways, connected by an ethylene chain to a positively charged quaternary ammonium center that is paired with a negatively charged carboxylate group within the same molecule. In materials science and polymer research laboratories, this monomer is used to create strongly hydrophilic surfaces, hydrogels, and polymer coatings that are recognized for their ability to resist protein and cell attachment.

The property that makes this monomer sought after is its zwitterionic character, which produces an overall neutral charge while still interacting very strongly with water molecules through electrostatic bonding. The dense hydration layer that forms as a result is the basis for the antifouling behavior observed in materials made from it. The methacrylate group at the end of the molecule makes it compatible with the various radical polymerization techniques already common in laboratories, including controlled radical polymerization for growing polymer brushes from substrate surfaces.

In Indonesian laboratories, this monomer is typically encountered in materials science and polymer research programs at universities and research institutes, where work focuses on surface modification, hydrogel formulation, and the preparation of functional coatings. It is handled as a research-scale reagent within polymer synthesis workflows, used together with radical initiators and standard laboratory polymerization equipment rather than in routine analytical testing.

TCI brochures (PDF)

Zwitterionic Monomers Suitable for Biocompatible Polymer Synthesis 2024-08-06 · p. 1
Biomaterials Research Reagents 2025-02-19 · p. 10
Monomers 2025-05-28 · p. 8

Related TCI products

Antifouling surface coating preparation, because the zwitterionic structure builds a dense hydration layer that resists the attachment of proteins and cells on treated surfaces.
Hydrogel synthesis, because the strongly hydrophilic carboxybetaine group interacts intensely with water and supports highly hydrated polymer networks for materials research.
Surface-initiated controlled radical polymerization, because the terminal methacrylate group allows polymer brushes to be grown directly from a substrate surface under controlled conditions.
Copolymer development in polymer chemistry, because the methacrylate functionality is compatible with the common free radical polymerization techniques already established in laboratory practice.
Biointerface and materials science studies, because the overall neutral charge combined with strong water interaction makes it useful for investigating protein-resistant and cell-resistant material behavior.

From the TCI brochure

Low protein absorption polymer
Biocompatible micelle
Biological substance sensor

Brand	TCI
CAS number	62723-61-9
Molecular formula	—
Purity	—
Category	Materials Science > Polymer/Macromolecule Reagents > Monomers
Pack sizes	available in standard research laboratory pack sizes; please confirm the currently offered size when ordering
Physical form	—
Storage	store according to the conditions stated on the manufacturer label and accompanying safety data sheet

Product code: M3185

Store this monomer in its original tightly closed container, kept in a cool, dry, and well ventilated area away from heat sources, direct sunlight, and ignition sources, following the conditions stated on the manufacturer label and safety data sheet. As a polymerizable methacrylate monomer, it should be protected from elevated temperatures that may promote unintended polymerization during storage. Handle it in a fume hood using gloves, safety glasses, and a laboratory coat, and avoid contact with skin and eyes as well as inhalation of any vapor or dust. Keep containers clearly labeled, close them immediately after use, and dispose of residues and contaminated materials through the laboratory chemical waste procedure. Always review the safety data sheet before opening a new container.

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