TCI B6486, Boc-DL-Phe-OH (CAS 4530-18-1), is racemic phenylalanine protected at the amino group with a tert-butoxycarbonyl group. The Boc group is stable to basic and nucleophilic conditions yet readily removed under acidic treatment, making this a dependable building block for solution- and solid-phase peptide synthesis. Its racemic nature makes it particularly cost-effective for coupling method development, chiral analysis reference work, and advanced teaching laboratories. AMI Scientific offers this TCI product in 25 g and 100 g pack sizes, to be stored cool, dry, and tightly closed.
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- Rodriguez et al. (1990). A general route to “carba” peptide bond replacements: Unequivocal synthesis of Boc--Phe-ψ(CH2-CH2)--Ala-OH and Boc--Phe-ψ(CH2-CH2)--Ala-OH.. Tetrahedron Letters doi:10.1016/s0040-4039(00)97829-8
- Hayashi et al. (2014). Development of potent antagonists for formyl peptide receptor 1 based on Boc-Phe-d-Leu-Phe-d-Leu-Phe-OH. Bioorganic & Medicinal Chemistry doi:10.1016/j.bmc.2014.06.048
- Karle et al. (2002). Infinite pleated β-sheet formed by the β-hairpin Boc-β-Phe-β-Phe- d -Pro-Gly-β-Phe-β-Phe-OMe. Proceedings of the National Academy of Sciences doi:10.1073/pnas.022616499
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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