Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.
Couldn't load pickup availability
Description
TCI E1555 Erythromycylamine is an amino derivative of erythromycin, a macrolide-class antibiotic built around a fourteen-membered lactone ring bearing two attached sugar units. In this compound, the ketone group at position nine has been replaced by an amine group, a change that alters the chemical character of the molecule while also opening a route for further modification. In the laboratory, Erythromycylamine is used as a reference material in antibiotic research, as a synthetic precursor for macrolide derivatives, and as a comparison compound in microbiological and medicinal chemistry studies that examine the relationship between structure and antibacterial activity.
The property that makes this compound a preferred choice is the presence of a free amine group on the macrolide framework. That group is both nucleophilic and basic, so it can be reacted with aldehydes and ketones to form oxazine derivatives and other structures, a route widely recognised in the development of later-generation macrolides. Replacing the ketone with an amine also improves the stability of the framework under acidic conditions compared with the parent erythromycin, because it reduces the tendency toward internal hemiketal formation. This additional basic character further distinguishes the compound's behaviour from that of its parent molecule.
In Indonesian laboratories, Erythromycylamine is typically encountered in academic pharmacy and chemistry faculties, in pharmaceutical research and development units, and in microbiology laboratories carrying out antibacterial testing. It generally appears in work where a defined macrolide framework is required as a starting point for synthesis or as a comparison compound alongside other antibiotics, and it is usually handled in small quantities within research-scale rather than production-scale workflows.
Laboratory Applications
Antibiotic reference research: the defined macrolide framework allows results from antibacterial work to be compared against a consistent structural standard rather than an undefined material.
Synthesis of macrolide derivatives: the free amine at position nine serves as a reactive handle for building later-generation macrolide structures from a well-characterised starting framework.
Oxazine derivative preparation: the nucleophilic amine group reacts with aldehydes and ketones, providing direct access to oxazine rings and related modified macrolide structures.
Structure-activity relationship studies: the single ketone-to-amine substitution relative to erythromycin makes it a valuable probe for correlating structural change with antibacterial behaviour.
Microbiological comparison work: the compound acts as a companion reference alongside other antibiotics when evaluating the antibacterial response of macrolide-type structures in test systems.
Specifications
Brand: TCI (Tokyo Chemical Industry)
CAS Number: 26116-56-3
Category: Life Science > Biochemicals and Reagents > Antibiotics
Catalogue Number: E1555
Pack sizes: available in research-scale laboratory pack sizes; please confirm the currently listed options when ordering
Storage: keep in a cool, dry place in a tightly closed container, following the storage instructions supplied with the product
Handling and Storage
Store Erythromycylamine in its original tightly closed container, kept in a cool, dry and well-ventilated place away from direct sunlight, moisture and sources of heat. Amber glass or the supplier's original packaging is suitable, since exposure to air and humidity should be limited during storage and after each use. Handle the material in a fume hood or a well-ventilated working area, wearing gloves, safety glasses and a laboratory coat, and avoid generating dust when weighing out portions. Close the container promptly after sampling, label any prepared solutions clearly, and always consult the safety data sheet supplied with the product before use and before disposal.
