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TCI

CAS 10420-73-2

6-Chloroflavone TCI C3066

6-Chloroflavone TCI C3066
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Description

TCI C3066 6-Chloroflavone is a flavone derivative — a heterocyclic compound built on the 2-phenyl-4H-chromen-4-one core and carrying a chlorine substituent at position 6 of the benzopyranone ring. Flavone forms the structural backbone of the large flavonoid family, a group of compounds widely distributed in nature and an important subject of study in natural product chemistry, medicinal chemistry, and food science. As a synthetic starting material with a clearly defined structure, this compound allows researchers to construct halogenated flavone derivatives without going through the lengthy and low-yielding isolation steps required when working from plant sources.

What makes this material attractive is the combination of a stable, rigid flavone framework with a chlorine atom that serves as a point for further modification. The carbonyl group at position 4 and the conjugated double bond system give the molecule characteristic electronic properties that are readily observed by ultraviolet-visible spectroscopy and by fluorescence measurement, which also makes the compound useful as a model chromophore. The chlorine substituent influences the electron density distribution across the aromatic ring and increases the lipophilicity of the molecule — two factors frequently examined when researchers investigate structure-property and structure-activity relationships.

In Indonesian laboratories, this building block is typically used in university and institutional research settings where synthetic organic chemistry, natural product chemistry, and medicinal chemistry programmes overlap. It supports postgraduate research projects, method development work, and reference preparation for analytical studies of flavonoid compounds. Because it arrives as a defined synthetic material rather than a plant extract, it fits well into laboratories that need reproducible starting points for derivative synthesis and for building comparison data across experiments.

Laboratory Applications

  • Synthesis of halogenated flavone derivatives — the chlorine substituent at position 6 provides a defined handle for further functionalisation, letting chemists build a derivative series from a consistent, well-characterised starting structure.
  • Structure-activity relationship studies — the compound allows systematic comparison of how a chlorine substituent alters electron density and lipophilicity relative to the unsubstituted flavone core in medicinal chemistry investigations.
  • Reference material for natural product chemistry — as a defined flavone-class compound, it supports comparative work in flavonoid research without requiring the lengthy plant isolation procedures that give low yields.
  • Chromophore and spectroscopic model studies — the conjugated system and position-4 carbonyl produce characteristic ultraviolet-visible and fluorescence responses suitable for teaching and for method development in optical measurement.
  • Building block for medicinal chemistry screening libraries — the rigid benzopyranone framework serves as a starting scaffold for preparing candidate compounds intended for biological evaluation in academic research programmes.

Specifications

  • Brand: TCI (Tokyo Chemical Industry)
  • CAS Number: 10420-73-2
  • Product Code: C3066
  • Chemical Class: Flavone derivative; 2-phenyl-4H-chromen-4-one core with chlorine at position 6
  • Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
  • Pack Sizes: available in the pack sizes listed for this catalogue item — please confirm the required size when ordering
  • Storage: store in a closed container in a cool, dry place away from light; refer to the manufacturer's product label and safety data sheet for the specific storage condition assigned to this item

Handling and Storage

Store this material in its original tightly closed container, kept in a cool, dry, well-ventilated area and protected from direct sunlight and sources of heat or ignition. Amber glass or the manufacturer's supplied packaging is suitable for limiting light exposure of the conjugated chromophore system. Handle in a fume hood using standard laboratory personal protective equipment — safety glasses, a laboratory coat, and appropriate chemical-resistant gloves — and avoid generating dust when weighing the solid. Keep the container closed when not in use to prevent moisture uptake and contamination, and return it promptly to its designated storage location. Always consult the manufacturer's safety data sheet before use, and dispose of residues and contaminated materials through the laboratory's established chemical waste procedure in accordance with applicable regulations.

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