• 2,6-Dimethylquinoline (CAS 877-43-0) - TCI D1236 - AMI Scientific
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TCI

CAS 877-43-0

2,6-Dimethylquinoline TCI D1236

2,6-Dimethylquinoline TCI D1236
Rp 2.450.700,00
Rp 2.450.700,00
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TCI D1236 2,6-Dimethylquinoline is a nitrogen-containing heterocyclic compound built on a quinoline framework bearing two methyl groups. In the laboratory, compounds of the quinoline class serve as important building blocks because their skeleton is frequently encountered in bioactive molecules, dyes, and ligands for coordination chemistry. The nitrogen atom in the ring imparts weakly basic character together with the ability to bind metals, while the fused benzene ring provides aromatic stability. This combination makes it a material regularly used by synthesis researchers to construct larger target structures and to study the chemical behaviour of heterocyclic systems.

The property that leads researchers to select this compound is the methyl substitution pattern at the two and six positions. The methyl group at position two sits directly adjacent to the nitrogen atom, so it influences electron density while also introducing steric hindrance around the coordination centre. The methyl group on the benzene ring, in turn, alters the electronic character and the overall solubility of the molecule. The methyl groups can also serve as starting points for further transformation, for example through reactions at the benzylic position, giving the compound useful synthetic versatility.

In Indonesian laboratories, this material is typically used in organic synthesis research at universities, government research institutes, and industrial R&D units. It is generally handled at bench scale for exploratory reaction work, method development, and the preparation of intermediates, rather than in bulk production. Researchers commonly work with it inside a fume hood using standard glassware, and store the remaining material carefully between experiments so that a single pack can support an extended series of studies.

  • Heterocyclic building block synthesis: the quinoline core provides a ready-made bicyclic framework that researchers can elaborate into larger nitrogen-containing target structures without constructing the ring system from scratch.
  • Ligand preparation for coordination chemistry: the ring nitrogen offers a metal-binding site while the adjacent 2-methyl group supplies steric bulk around the coordination centre, allowing tuning of metal complex behaviour.
  • Benzylic functionalisation studies: both methyl groups act as convenient handles for further transformation, making the compound suitable for exploring reactions that proceed at benzylic positions.
  • Structure–reactivity investigations: the defined substitution pattern lets researchers examine how methyl groups influence electron density, basicity, and reactivity within a heterocyclic aromatic system.
  • Intermediate preparation for bioactive and dye-related research: because the quinoline skeleton appears widely in bioactive molecules and colourants, this compound serves as a starting material in exploratory work in those areas.

Brand TCI
CAS number 877-43-0
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes available in standard laboratory research pack sizes; please confirm the size options when ordering
Physical form —
Storage keep in a tightly closed original container, protected from light and heat
  • Chemical class: nitrogen-containing heterocyclic compound, quinoline derivative with methyl substitution at positions 2 and 6

Store the container tightly closed in a cool, dry, and well-ventilated area, away from heat sources, direct sunlight, and incompatible chemicals. Keep the material in its original supplier container, or in a chemically compatible closed container that is clearly labelled, and reseal it immediately after each use to limit exposure to air and moisture. Handle the compound in a fume hood while wearing safety glasses, gloves, and a laboratory coat, and avoid inhalation of dust or vapour and contact with skin and eyes. Consult the manufacturer's safety data sheet before use, and dispose of residues and contaminated materials in accordance with applicable chemical waste procedures.

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