N,N-Dimethylsulfamide TCI D2640

Name: TCI D2640 3984-14-3 N,N-Dimethylsulfamide
Brand: TCI
SKU: TCI2510D264022941
Price: 2008650.0 IDR
Availability: InStock

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Berat 1g 5g

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Description

TCI D2640 N,N-Dimethylsulfamide with CAS number 3984-14-3 is a sulfamide compound in which a sulfonyl group sits between two nitrogen atoms, one nitrogen carrying two methyl groups while the other remains free. The material is classified as a non-heterocyclic building block and serves as a ready-to-use source of the sulfamide motif, a structural pattern found frequently in bioactive compounds and active pharmaceutical ingredients. In the laboratory, this compound saves synthetic steps because researchers no longer need to construct the sulfamide group from sulfuryl chloride, a reagent that is considerably more difficult to handle and demands strict reaction conditions.

The characteristic that makes this compound a preferred choice is the presence of a free nitrogen group that remains available for functionalization, while the other side is already locked as a dimethylamine unit. This asymmetric structure allows directed modification without the risk of double reaction that would confound the outcome. The sulfonyl group is a strong electron-withdrawing group, so the proton on the free nitrogen is sufficiently acidic and readily removed with a moderate base, opening the way to both alkylation and arylation reactions. In addition, the sulfamide motif is known as a good hydrogen-bond acceptor and is comparatively robust.

In Indonesian laboratories, TCI D2640 is typically used in synthetic and medicinal chemistry research groups that build sulfamide-containing target molecules, whether at universities, government research institutes, or industrial R&D units. It suits work programmes where a reliable sulfamide starting point is preferred over generating the group in-house, since the reagent avoids the handling burden and tight reaction control associated with sulfuryl chloride routes, and supports step-efficient exploratory synthesis on a laboratory scale.

Laboratory Applications

Sulfamide motif installation — provides the complete sulfamide pattern in a single reagent, so the target structure can be assembled without building the group from scratch.
Medicinal chemistry building block work — supplies a structural pattern commonly present in bioactive compounds and active pharmaceutical ingredients, making it useful for preparing candidate molecules and analogues.
Selective N-alkylation — the free nitrogen can be deprotonated with a moderate base thanks to the electron-withdrawing sulfonyl group, allowing alkyl groups to be introduced in a controlled way.
N-arylation chemistry — the same acidic free N–H permits arylation, while the dimethylated nitrogen stays locked and prevents unwanted double substitution on both sides.
Hydrogen-bond acceptor design — the sulfamide motif acts as a good hydrogen-bond acceptor with comparatively good stability, useful when studying molecular recognition or binding interactions.

Specifications

Brand: TCI (Tokyo Chemical Industry)
CAS number: 3984-14-3
Chemical name: N,N-Dimethylsulfamide
Catalogue number: D2640
Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes: available in standard TCI laboratory research pack sizes; please confirm the size required when ordering
Storage: keep in the originally supplied closed container under the storage conditions stated on the manufacturer's label and Safety Data Sheet

Handling and Storage

Store the material in its original tightly closed container, in a cool, dry, and well-ventilated area away from moisture, direct sunlight, and incompatible reagents, following the storage conditions stated on the manufacturer's label and Safety Data Sheet. Keep the container closed when not in use to prevent moisture uptake and contamination. Handle the compound in a fume hood, wearing safety glasses, chemical-resistant gloves, and a laboratory coat, and avoid inhalation of dust and contact with skin and eyes. Weigh and transfer using clean, dry, chemically compatible labware. Review the Safety Data Sheet before first use, and dispose of residues and contaminated materials through the laboratory's chemical waste procedures.