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Description
TCI D2664 2,4'-Dihydroxybenzophenone (CAS 606-12-2) is a benzophenone-class compound carrying two phenolic hydroxyl groups: one located ortho to the carbonyl group on the first ring, and one at the para position on the second ring. This asymmetric arrangement gives the molecule its characteristic ability to absorb ultraviolet light, because the ortho hydroxyl group can form an intramolecular hydrogen bond with the carbonyl group and thereby open a non-radiative energy decay pathway. In the laboratory, the compound serves as a starting material and as a reference compound in research on ultraviolet absorbers, photochemistry, and materials chemistry.
The properties that make this material a preferred choice are the combination of its photophysical behaviour and the presence of two reactive phenol groups. The para hydroxyl group on the second ring is the more accessible of the two and is readily alkylated or acylated, so researchers can attach side chains to adjust solubility or to anchor the molecule onto a polymer. The ortho hydroxyl group, by contrast, should be preserved, since it is precisely this group that supports the compound's capacity to dissipate ultraviolet energy. The benzophenone framework is also well known as a photoinitiator and sensitizer in photochemical reactions, which makes the compound of further interest to synthetic and materials researchers.
In Indonesian laboratories, this building block is typically used in university and institutional research settings as well as in industrial development work, where it supports synthetic routes toward ultraviolet-absorbing additives and functionalized benzophenone derivatives. It is handled on a research and development scale, weighed out for small-batch reactions, and used as a comparison standard in photochemical and analytical studies. Its position within the non-heterocyclic building block category reflects this role as a versatile intermediate rather than a finished formulation ingredient.
Laboratory Applications
Ultraviolet absorber research: the ortho hydroxyl and carbonyl pairing provides the intramolecular hydrogen bond and non-radiative decay pathway that defines ultraviolet-absorbing behaviour under study.
Photochemistry studies: the benzophenone framework is a recognized photoinitiator and sensitizer, so the compound is useful for investigating light-driven reactions and energy transfer processes.
Materials chemistry synthesis: the reactive para phenol allows the molecule to be anchored onto polymers, letting researchers build ultraviolet-protective functionality directly into a material.
Selective derivatization work: alkylation or acylation at the more accessible para hydroxyl group permits side chain installation for solubility tuning while the ortho hydroxyl remains intact.
Reference compound applications: the compound serves as a comparison and standard material in photochemical, photophysical, and materials characterization studies requiring a defined benzophenone structure.
Specifications
Brand: TCI (Tokyo Chemical Industry)
CAS Number: 606-12-2
Catalog Number: D2664
Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes: available in standard research and laboratory pack sizes; please confirm the currently offered packaging when ordering
Storage: keep in a tightly closed container, protected from light, in a cool and dry place
Handling and Storage
Store the container tightly closed in a cool, dry, and well-ventilated area, protected from direct light and away from heat sources and incompatible chemicals. Original manufacturer packaging is the most suitable container; where transfer is necessary, use clean amber glass or another chemically compatible closed vessel, clearly labelled with the compound name and CAS number. As with any phenolic organic building block, handle the material in a fume hood or a well-ventilated workspace, wear safety glasses, gloves, and a laboratory coat, and avoid inhaling dust or allowing contact with skin and eyes. Keep the container closed when not in use to limit moisture uptake, and consult the manufacturer's safety data sheet before first use and before disposal of residues.
