2,4-Dimethylbenzophenone TCI D3458

Name: TCI D3458 1140-14-3 2,4-Dimethylbenzophenone
Brand: TCI
SKU: TCI2510D345823743
Price: 3541650.0 IDR
Availability: InStock

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Berat 25g

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Description

TCI D3458 2,4-Dimethylbenzophenone is an aromatic ketone belonging to the benzophenone family, supplied for use as a non-heterocyclic building block across a wide range of laboratory synthesis activities. Its basic structure consists of two aromatic rings bridged by a carbonyl group, with two methyl groups substituted at the 2- and 4-positions of one of those rings. This arrangement makes the compound of interest both as a synthetic intermediate and as a model molecule in photochemical studies, since aromatic carbonyl groups are known to absorb ultraviolet light and undergo excitation to the triplet excited state.

The principal reason for selecting this material is the reactivity of the aromatic carbonyl group, which can readily be directed into many classical transformations: nucleophilic addition by organometallic reagents, reduction to a secondary benzylic alcohol, Wittig-type olefination, and the formation of oxime and hydrazone derivatives. At the same time, the two methyl groups impart characteristic steric hindrance and electron-donating electronic effects, while also providing benzylic positions that can be functionalised further through halogenation or oxidation. The asymmetric substitution pattern at the 2- and 4-positions is likewise frequently exploited when a defined, non-symmetrical aromatic framework is required.

In Indonesian laboratories, this building block is typically used in university and institutional research settings where organic synthesis, structural derivatisation, and photochemistry are studied on a bench scale. It is generally drawn upon for the preparation of intermediates, for method development and reaction optimisation work, and as a reference structure in teaching and research on aromatic carbonyl reactivity. Because it is supplied as a TCI catalogue item, it fits routine procurement for laboratories that require consistent, well-identified reagents for repeatable synthetic work.

Laboratory Applications

Nucleophilic addition chemistry: the aromatic carbonyl group readily accepts organometallic reagents, allowing controlled construction of tertiary alcohols and more elaborated carbon frameworks from a single starting material.
Carbonyl reduction studies: the ketone can be reduced to a secondary benzylic alcohol, making it a convenient substrate for comparing reducing agents, catalysts, and stereochemical or selectivity outcomes.
Wittig-type olefination: the reactive carbonyl centre serves as a dependable partner for converting the ketone into substituted alkenes when extended conjugated or olefinic targets are being assembled.
Oxime and hydrazone derivative preparation: condensation at the carbonyl group gives nitrogen-containing derivatives useful for characterisation work and as intermediates toward further heteroatom-bearing structures.
Photochemical model studies: because the aromatic carbonyl absorbs ultraviolet light and reaches a triplet excited state, the compound suits investigations of excitation behaviour and photoinduced reaction pathways.

Specifications

Brand: TCI (Tokyo Chemical Industry)
Catalogue reference: D3458
CAS number: 1140-14-3
Chemical name: 2,4-Dimethylbenzophenone
Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes: available in standard TCI research-scale catalogue packs; please confirm the size required when ordering
Storage: keep in the original, tightly closed container as indicated on the manufacturer's label

Handling and Storage

Store the container tightly closed in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and ignition sources. Because the aromatic carbonyl group is light-absorbing, keeping the material in its original amber or opaque container and protecting it from prolonged light exposure is advisable. Handle the compound in a fume hood or a well-ventilated workspace, and wear standard personal protective equipment including safety glasses, chemically resistant gloves, and a laboratory coat. Avoid dust generation, inhalation, and contact with skin and eyes; use clean, dry glass or otherwise chemically compatible labware for transfer and weighing. Keep the material separated from strong oxidising agents and other incompatible chemicals, label all secondary containers clearly, and dispose of residues and contaminated materials in accordance with applicable institutional and local chemical waste procedures. Always consult the manufacturer's Safety Data Sheet before use.