Elvitegravir TCI E1589

Name: TCI E1589 697761-98-1 Elvitegravir
Brand: TCI
SKU: TCI2510E158929639
Price: 6582450.0 IDR
Availability: InStock

Rp 6.582.450,00

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Berat 250mg

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Description

Elvitegravir is an antiviral compound belonging to the class of HIV-1 integrase strand transfer inhibitors, known in the research literature as INSTIs. The compound works by binding to the complex formed between integrase and viral DNA, thereby blocking the step in which viral genetic material is inserted into the host cell genome. In the laboratory, this material is used as a research reagent and as a comparator compound in studies of molecular virology, integrase enzyme biochemistry, and the development of new antiviral screening assays.

The property that makes this compound a widely preferred choice is its highly specific mechanism of action against a single viral enzyme, which produces a clean inhibition signal that is straightforward to interpret in biochemical experiments. As a small molecule from the quinolone carboxylate family, the compound carries a metal-ion binding group that coordinates with magnesium ions at the integrase active site — a pharmacophore feature that serves as a reference point in the design of next-generation inhibitors. Its activity profile has been extensively documented in the scientific literature, so experimental results can be compared against published data.

In Indonesia, materials such as this one are used by research laboratories working on infectious disease, by university biochemistry and molecular biology groups, and by institutional facilities that run enzyme inhibition and antiviral screening work. It typically serves as a reference inhibitor in assay development and method validation, where a well-characterized compound with a documented activity profile allows local results to be checked against the published record before new candidate molecules are evaluated.

Laboratory Applications

HIV-1 integrase inhibition assays — serves as a reference inhibitor whose documented, enzyme-specific activity provides a reliable benchmark against which candidate compounds can be ranked.
Antiviral screening assay development — its clean, single-target inhibition signal makes it well suited to validating new screening formats before unknown test compounds are introduced.
Molecular virology research — supports mechanistic studies of the strand transfer step, since the compound blocks insertion of viral genetic material into the host genome.
Enzyme biochemistry studies — the metal-ion binding group coordinating magnesium at the integrase active site makes it useful for probing active-site chemistry and inhibitor binding.
Structure–activity and inhibitor design work — as an established quinolone carboxylate pharmacophore reference, it guides comparison studies during design of next-generation integrase inhibitors.

Specifications

Brand: TCI
CAS number: 697761-98-1
Catalogue number: E1589
Category: Life Science > Biochemicals and Reagents > Antibiotics
Pack sizes: available in standard research-scale catalogue pack sizes; please confirm the current options when ordering
Storage: store according to the manufacturer's instructions stated on the product label and Safety Data Sheet

Handling and Storage

Store the material in its original tightly closed container, kept in a cool, dry, well-ventilated place and protected from light and moisture unless the manufacturer's label specifies otherwise. Amber glass or the supplied original packaging is suitable for storage; solutions prepared for assay work should be kept in clearly labelled, chemically compatible vials. Handle the compound in a fume hood or well-ventilated area using gloves, safety glasses, and a laboratory coat, and avoid generating dust when weighing. As a biologically active research compound, it is intended for laboratory research use only and should be handled by trained personnel. Review the Safety Data Sheet before first use and dispose of residues and contaminated materials in accordance with applicable laboratory waste regulations.