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TCI B6776 (CAS 1402232-83-0) is a Boc-protected fluorinated spiro[piperidine-quinoline] building block designed for medicinal chemistry programs. Its rigid, sp3-rich spirocyclic core offers three-dimensional character that is valuable for exploring new chemical space. The free anilinic nitrogen provides a convenient handle for acylation, sulfonylation, or alkylation during library synthesis. AMI Scientific offers this TCI reagent in a 100 mg pack size for research-scale synthesis.
TCI brochures (PDF)
- Building Blocks for Medicinal Chemistry 2025-05-12 · p. 1
Related TCI products
- TCI E1180 100491-29-0 Ethyl 7-Chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
- TCI B6777 1402232-95-4 tert-Butyl 5'-Fluoro-1',4'-dihydro-2'H-spiro[piperidine-4,3'-quinoline]-1-carboxylate
- TCI C2650 100361-18-0 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid
- TCI C2293 86393-33-1 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
- TCI C3067 23779-97-7 4-Chloro-8-(trifluoromethyl)quinoline
- TCI F0944 84163-13-3 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole Hydrochloride
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- Meng et al. (2017). tert-Butyl (2S,3R,4R)-7′-bromo-4-methyl-2′,5-dioxo-4,5-dihydro-3H-spiro[furan-2,3′-indoline]-3-carboxylate. IUCrData doi:10.1107/s2414314617004126
- Hoffmann et al. (1998). Separation of (R)‐ and (S)‐tert‐butyl 2‐tert‐butyl‐4‐methoxy‐2,5‐dihydro‐1,3‐imidazole‐1‐carboxylate (building block for amino acid synthesis) by preparative high performance liquid chromatography on a polysaccharide stationary phase. Chirality doi:10.1002/(sici)1520-636x(1998)10:3<217::aid-chir3>3.3.co;2-r
- K. dkk. (2025). Synthesis and Characterization of tert-butyl 3-(((2-hydroxynaphthalen1-yl)methylene)amino)-4-(4-(trifluoromethyl)phenyl)piperidine-1- carboxylate: A piperidine clubbed Boc protected versatile building block for multi functionalized chemical reactions. Journal of Applied Research and Technology doi:10.22201/icat.24486736e.2025.23.1.2611
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
Produk Terkait
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Ethyl7-Chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate TCI E1180
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tert-Butyl5'-Fluoro-1',4'-dihydro-2'H-spiro[piperidine-4,3'-quinoline]-1-carboxylate TCI B6777
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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylicAcid TCI C2650
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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylicAcid TCI C2293
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4-Chloro-8-(trifluoromethyl)quinoline TCI C3067
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6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazoleHydrochloride TCI F0944
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2-Phenyl-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one TCI P3118
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![tert-Butyl 5'-Fluoro-1',4'-dihydro-2'H-spiro[piperidine-4,3'-quinoline]-1-carboxylate (CAS 1402232-95-4) - TCI B6777 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510B6777.jpg?v=1768816103&width=533)
