tert-Butyl 7'-Fluoro-1',4'-dihydro-2'H-spiro[piperidine-4,3'-quinoline]-1-carboxylate TCI B6776

Name: TCI B6776 1402232-83-0 tert-Butyl 7'-Fluoro-1',4'-dihydro-2'H-spiro[piperidine-4,3'-quinoline]-1-carboxylate
Brand: TCI
SKU: TCI2510B677613697
Price: 7998900.0 IDR
Availability: InStock

Rp 7.998.900,00

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Berat 100mg

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Description

TCI B6776 (CAS 1402232-83-0) is a Boc-protected fluorinated spiro[piperidine-quinoline] building block designed for medicinal chemistry programs. Its rigid, sp3-rich spirocyclic core offers three-dimensional character that is valuable for exploring new chemical space. The free anilinic nitrogen provides a convenient handle for acylation, sulfonylation, or alkylation during library synthesis. AMI Scientific offers this TCI reagent in a 100 mg pack size for research-scale synthesis.

Scientific References

Meng et al. (2017). tert-Butyl (2S,3R,4R)-7′-bromo-4-methyl-2′,5-dioxo-4,5-dihydro-3H-spiro[furan-2,3′-indoline]-3-carboxylate. IUCrData doi:10.1107/s2414314617004126
Hoffmann et al. (1998). Separation of (R)‐ and (S)‐tert‐butyl 2‐tert‐butyl‐4‐methoxy‐2,5‐dihydro‐1,3‐imidazole‐1‐carboxylate (building block for amino acid synthesis) by preparative high performance liquid chromatography on a polysaccharide stationary phase. Chirality doi:10.1002/(sici)1520-636x(1998)10:3<217::aid-chir3>3.3.co;2-r
K. dkk. (2025). Synthesis and Characterization of tert-butyl 3-(((2-hydroxynaphthalen1-yl)methylene)amino)-4-(4-(trifluoromethyl)phenyl)piperidine-1- carboxylate: A piperidine clubbed Boc protected versatile building block for multi functionalized chemical reactions. Journal of Applied Research and Technology doi:10.22201/icat.24486736e.2025.23.1.2611

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.