• SB 222200 (CAS 174635-69-9) - TCI B6551 - AMI Scientific
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TCI

CAS 174635-69-9

SB 222200 TCI B6551

SB 222200 TCI B6551
Rp 5.106.150,00
Rp 5.106.150,00
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SB 222200 (CAS 174635-69-9) is a research compound described in the pharmacological literature as a selective tachykinin NK-3 receptor antagonist. Its subtype selectivity makes it a useful tool for distinguishing NK-3-mediated signalling from NK-1 and NK-2 pathways in receptor binding assays, cell-based functional studies, and approved animal models. Stock solutions are typically prepared in DMSO, aliquoted, and stored frozen to avoid repeated freeze–thaw cycles, with the vial allowed to reach room temperature before opening. AMI Scientific supplies a 10 mg pack size strictly for research and experimental use in accordance with institutional safety and ethics requirements.

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  • King et al. (2005). Effect of a selective and potent central nervous system penetrant, neurokinin-3 receptor antagonist (SB-222200), on cisplatin-induced emesis in the ferret. Neuroscience Letters doi:10.1016/j.neulet.2004.11.015
  • Bennacef et al. (2007). Functionalization through Lithiation of (S)-N-(1-Phenylpropyl)-2-phenylquinoline-4-carboxamide. Application to the Labeling with Carbon-11 of NK-3 Receptor Antagonist SB 222200. The Journal of Organic Chemistry doi:10.1021/jo062285p
  • Sarau et al. (2000). Nonpeptide Tachykinin Receptor Antagonists. II. Pharmacological and Pharmacokinetic Profile of SB-222200, a Central Nervous System Penetrant, Potent and Selective NK-3 Receptor Antagonist. The Journal of Pharmacology and Experimental Therapeutics doi:10.1016/s0022-3565(24)38912-8

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.

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