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TCI

CAS 1399008-27-5

N,N'-[(2S,2'S)-[(2-Iodo-1,3-phenylene)bis(oxy)]bis(propane-2,1-diyl)]bis(mesitylamide) TCI I1122

N,N'-[(2S,2'S)-[(2-Iodo-1,3-phenylene)bis(oxy)]bis(propane-2,1-diyl)]bis(mesitylamide) TCI I1122

Chemical Identity

CAS No.
1399008-27-5
PubChem
CID 66548671·SID 468592108
Formula
C32H39IN2O4
Molecular weight
642.6 g/mol
Purity
>96.0%(HPLC)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
N-[(2S)-2-[2-iodo-3-[(2S)-1-[(2,4,6-trimethylbenzoyl)amino]propan-2-yl]oxyphenoxy]propyl]-2,4,6-trimethylbenzamide
SMILES
CC1=CC(=C(C(=C1)C)C(=O)NC[C@H](C)OC2=C(C(=CC=C2)O[C@@H](C)CNC(=O)C3=C(C=C(C=C3C)C)C)I)C
InChIKey
JAYNHBKHWBZEMW-DQEYMECFSA-N
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TCI I1122 1399008-27-5 is a complex chemical compound used in asymmetric synthesis, playing a vital role in laboratories that require precise control over stereochemistry. This chiral catalyst or ligand is essential for producing compounds with specific asymmetric structures, which are critical in pharmaceutical and organic chemistry research. Its unique molecular structure allows it to direct reactions toward the desired product, making it a valuable tool for researchers aiming to achieve high-purity synthetic outcomes.

The compound's stability under specific conditions and its ability to enhance reaction efficiency make it a preferred choice in modern chemical laboratories. Its complex molecular architecture enables it to interact effectively with various substrates, facilitating the synthesis of chiral compounds with high selectivity. This stability ensures that it remains effective across different experimental setups, providing consistent results. Its reliability and performance in controlled environments further solidify its position as a key reagent in asymmetric synthesis.

In Indonesian laboratories, this compound is widely used by chemists engaged in asymmetric synthesis, particularly in research related to drug development, organic compounds, and complex molecules. Its availability and adherence to international quality standards make it a trusted choice for researchers seeking reliable and high-quality reagents. The compound's versatility and effectiveness in achieving specific stereochemical outcomes make it an essential component in many chemical research projects.

Advantages (TCI brochure)

  • Useful for high yielding and highly enantioselective asymmetric spirolactonizations
  • Applicable to one-pot Diels-Alder reactions
  • Utilized in the asymmetric synthesis of acetonides

TCI brochures (PDF)

  • Asymmetric synthesis for the production of specific drug compounds requiring precise stereochemical control.
  • Organic chemistry research focused on the development of chiral molecules with high enantiomeric purity.
  • Advanced chemical reactions that demand controlled stereoselectivity and efficient catalytic activity.
  • Synthesis of complex organic structures where chiral reagents are necessary for achieving desired product configurations.
  • Pharmaceutical research involving the creation of compounds with specific spatial arrangements for therapeutic applications.

From the TCI brochure

  • Asymmetric lactonization and Diels-Alder cycloaddition
  • Asymmetric acetalization

Brand TCI
CAS number 1399008-27-5
Molecular formula —
Purity —
Category Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents
Pack sizes —
Physical form —
Storage Store in a cool, dry place away from moisture and direct sunlight

Data from the TCI brochure

Ukuran kemasan200mg

Source: TCI brochure RR140 (2026-01-06)

This compound should be stored in a cool, dry environment to maintain its chemical stability and effectiveness. It is recommended to keep it in a sealed container to prevent exposure to moisture and air, which could potentially degrade its properties. Due to its complex molecular structure, it is important to handle it with care to avoid contamination. Laboratory personnel should ensure that the storage area is well-ventilated and free from sources of heat or direct light. Proper labeling of containers is essential to ensure safe handling and prevent accidental use. General laboratory precautions include wearing appropriate personal protective equipment when handling the compound to minimize any potential risks.

References cited in the TCI brochure

  1. Muhammet Uyanik. Hydrogen Bonding and Alcohol Effects in Asymmetric Hypervalent Iodine Catalysis: Enantioselective Oxidative Dearomatization of Phenols Angewandte Chemie International Edition, 2013. doi:10.1002/anie.201303559
  2. Muhammet Uyanik. Enantioselective Synthesis of Masked Benzoquinones Using Designer Chiral Hypervalent Organoiodine(III) Catalysis ACS Catalysis, 2016. doi:10.1021/acscatal.6b03380