Hydroxyapatite
Hydroxyapatite: Properties, Biomaterial Applications and Research Products
Hydroxyapatite is the calcium phosphate that forms the main mineral of bone and teeth. Being biocompatible, it is widely studied for bone scaffolds, implant coatings and adsorbents. Here are its properties, synthesis routes and research products.
- Ca₁₀(PO₄)₆(OH)₂chemical formula
- Ca/P = 1.67stoichiometric ratio
- Powder & nanoincluding 200 nm needle type
- Research scaleavailable at AMI Scientific
What is hydroxyapatite?
Hydroxyapatite (HA or HAp) is a calcium phosphate mineral with the formula Ca₁₀(PO₄)₆(OH)₂ and a Ca/P molar ratio of 1.67. It is the main inorganic component of bone and tooth enamel, so the body accepts it well. That is why HA is one of the most studied biomaterials: it is bioactive, supports bone-cell growth (osteoconductive) and can bond directly to bone tissue.
In Indonesia many studies synthesise HA from natural waste such as eggshells, seashells and fish bones. Commercial HA with defined purity and particle size is useful as a reference for such syntheses, for example to compare XRD patterns and Ca/P ratios.
Hydroxyapatite research applications
- Scaffolds and bone-defect fillers (bone graft substitutes).
- Coatings on titanium implants to speed up osseointegration.
- HA-polymer composites (chitosan, collagen, PLA) for tissue engineering.
- Drug and protein carriers.
- Adsorbents for heavy metals and fluoride in water treatment.
- Chromatography stationary phase for protein purification.
Commonly studied synthesis routes
| Method | Principle | Notes |
|---|---|---|
| Wet precipitation | Reacting calcium and phosphate sources at alkaline pH | Simple; pH and temperature control the phase |
| Sol-gel | Precursors form a gel that is then calcined | Homogeneous, small particle size |
| Hydrothermal | Crystallisation in a heated, pressurised autoclave | High crystallinity, controlled morphology |
| From natural sources | Calcining eggshell, shell or fish bone, then reacting with phosphate | Economical; check impurities (Mg, Na, carbonate) |
Hydroxyapatite products
Selected Nanografi products; check full specifications and pack sizes on each product page.
| Product | Best for | Price | Purchase |
|---|---|---|---|
| Needle-type hydroxyapatite nanopowder, 96%, 200 nm | Composites and scaffolds needing needle morphology | Rp 2.977.000 | Buy online |
| Hydroxyapatite nanopowder | Coatings, composites, drug carriers | Rp 2.125.000 | Buy online |
| Hydroxyapatite powder | Synthesis reference, adsorbent | Rp 2.242.000 | Buy online |
| Hydroxyapatite powder (another grade) | Another size/pack option | Rp 2.164.000 | Buy online |
Products are for research and laboratory use only, not for consumption or as finished cosmetic ingredients. Full specifications and SDS are on each product page.
Characterising your synthesis
The HA phase is usually confirmed by XRD and compared with a standard pattern. AMI Scientific offers an XRD analysis service for your powder samples.
Frequently asked questions
What is hydroxyapatite?
The calcium phosphate mineral Ca₁₀(PO₄)₆(OH)₂, the main inorganic component of bone and teeth, widely used as a biomaterial.
Can these products be used in toothpaste or cosmetics?
No. Products in our store are research and laboratory materials, not certified cosmetic or food raw materials.
What is the difference between nano and micro hydroxyapatite?
Nano HA has a larger surface area and higher reactivity, often chosen for composites and drug carriers; micron powder is easier to handle and compact.
How do I confirm my HA synthesis?
Compare the XRD pattern with an HA standard, measure the Ca/P ratio (EDS/XRF) and check phosphate and hydroxyl groups by FTIR.
Need help choosing?
Tell us about your samples, methods and budget. Our team will put together the equipment and supplies with a formal quotation.
