2,4-Dichlorobenzophenone from TCI is a diaryl ketone: a benzophenone carrying two chlorine atoms at the 2- and 4-positions of one of its phenyl rings. As a non-heterocyclic building block, it gives chemists a benzophenone framework that is already functionalised. That framework can be converted further into diaryl alcohols, amines, alkenes, or heterocyclic compounds. Halogenated benzophenone and diarylmethane motifs appear widely in pharmaceutical molecules, agrochemicals, and photoactive materials, so this compound serves as a practical starting point for building more complex targets in the synthetic laboratory.
Researchers choose this compound because its carbonyl group is reactive enough for reduction, Grignard addition, or reductive amination, while the two chlorine atoms provide extra handles for cross-coupling and aromatic substitution. Benzophenones are also known for their characteristic photochemistry: they absorb ultraviolet light and can act as photosensitisers. Chlorinated derivatives such as this one help researchers study how substituents influence that behaviour. Because the substitution sits on only one ring, the molecule is unsymmetrical, which also makes it useful for regioselectivity studies where chemists need to tell the two aromatic rings apart.
In Indonesian laboratories, 2,4-Dichlorobenzophenone supports medicinal chemistry research, the synthesis of agrochemical intermediates, and photochemistry projects at universities. Research groups exploring structure-activity relationships can use it to prepare series of halogenated diaryl compounds, while teaching and thesis laboratories can use it to demonstrate classic carbonyl chemistry on a substituted aromatic system. Supplied under the TCI brand, it gives Indonesian researchers a recognised reagent source for both exploratory synthesis and method development work.
Related TCI products
- Medicinal chemistry synthesis: the functionalised benzophenone core can be converted into diaryl alcohols, amines, or heterocycles, which suits building analogue libraries around halogenated pharmaceutical motifs.
- Agrochemical intermediate preparation: halogenated benzophenone and diarylmethane structures are common in agrochemicals, so this compound is a logical precursor for intermediates in that field.
- Carbonyl transformation studies: the reactive ketone group undergoes reduction, Grignard addition, and reductive amination, which makes it a convenient substrate for exploring and teaching these reactions.
- Cross-coupling and aromatic substitution: the two chlorine atoms provide extra reactive handles, so researchers can attach new groups to the ring and elaborate the molecule in several directions.
- Photochemistry and regioselectivity research: benzophenones absorb ultraviolet light and act as photosensitisers, and this unsymmetrical chlorinated derivative helps researchers study how substituents and ring position affect reactivity.
| Brand | TCI (product code D0342) |
|---|---|
| CAS number | 19811-05-3 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Non-Heterocyclic Building Blocks |
| Pack sizes | as listed in the current TCI catalogue for product D0342 |
| Physical form | refer to the TCI product specification sheet |
| Storage | follow the conditions stated on the TCI label and Safety Data Sheet |
Store 2,4-Dichlorobenzophenone in its original, tightly closed TCI container in a cool, dry, well-ventilated area, away from direct sunlight and incompatible materials such as strong oxidising agents. Because benzophenones absorb ultraviolet light, keeping the container away from strong light sources is sensible practice. Handle the compound in a fume hood or well-ventilated workspace. Wear standard personal protective equipment, including a lab coat, safety glasses, and chemical-resistant gloves, and avoid creating dust or breathing in vapours. Label any secondary containers clearly. Always consult the TCI Safety Data Sheet for specific hazard information, first-aid measures, and disposal requirements before use.
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