TCI D1409 2,2-Dibromopropane is a halogenated organic compound belonging to the alkyl bromide class, carrying two bromine atoms attached to the same carbon atom (the geminal position). The material serves as a non-heterocyclic building block — a small starting material that chemists use to assemble larger and more complex molecules. In organic synthesis laboratories, dihalide compounds such as this one act as a source of reactive leaving groups, so the propane skeleton they carry can be coupled to nucleophiles, joined to organometallic reagents, or converted into other functional groups through substitution and elimination reactions.
The characteristic that makes 2,2-Dibromopropane a preferred choice is its gem-dibromide arrangement on a tertiary carbon, which gives it distinctive reaction behaviour that differs from vicinal dihalides and from dihalides separated by a longer chain. The carbon–bromine bond is relatively easier to cleave than a carbon–chlorine bond, so the compound remains reactive under conditions that are not overly harsh, while still being stable enough to weigh out and handle as a matter of routine. Its molecular structure is simple and symmetrical, which means reaction products are easy to predict and straightforward to follow by NMR spectroscopy.
In Indonesian laboratories, this reagent fits the day-to-day work of university organic synthesis groups, research institutes, and industrial R&D units that build target molecules step by step. It is typically drawn on for small-scale bench reactions where a defined, reproducible alkylating fragment is needed, and for teaching and method-development work in which a predictable, well-behaved dihalide helps students and researchers trace a reaction mechanism clearly through spectroscopic analysis.
- Nucleophilic substitution studies — the two carbon–bromine bonds provide readily displaced leaving groups, allowing researchers to introduce the propane fragment onto a wide range of nucleophilic partners.
- Elimination reaction work — the geminal dihalide arrangement on a tertiary carbon supports elimination pathways that generate unsaturated products under conditions that are not excessively forcing.
- Organometallic reagent preparation — the reactive carbon–bromine bonds make this material a practical partner for coupling the propane skeleton to organometallic species during multi-step synthesis.
- Multi-step molecule construction — as a non-heterocyclic building block, it lets chemists assemble larger and more complex target structures from a small, well-defined starting fragment.
- Mechanistic teaching and method development — the simple, symmetrical structure yields predictable products that are easy to trace and confirm by NMR spectroscopy during reaction monitoring.
| Brand | TCI |
|---|---|
| CAS number | 594-16-1 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Non-Heterocyclic Building Blocks |
| Pack sizes | available in standard TCI laboratory packaging; please confirm the pack size options when ordering |
| Physical form | — |
| Storage | keep in the closed original container under the conditions stated on the product label and safety data sheet |
- Chemical class: halogenated organic compound, alkyl bromide (geminal dibromide)
Store the container tightly closed in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and ignition sources, and keep it separated from strong bases, strong oxidising agents, and reactive metals. Retain the material in its original manufacturer container, or transfer only into containers of chemically compatible material that are clearly labelled with the product name and CAS number. Handle the compound inside a functioning fume hood and wear appropriate personal protective equipment, including chemical-resistant gloves, safety goggles, and a laboratory coat. Avoid inhaling vapours and prevent contact with skin and eyes. Always consult the manufacturer's safety data sheet before use, and dispose of residues and contaminated materials as halogenated organic chemical waste in accordance with applicable laboratory waste procedures.
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