TCI
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Description
TCI D4030 3,4-Diaminofurazan is a heterocyclic building block containing a furazan ring, that is, a 1,2,5-oxadiazole core, carrying two neighbouring amino groups at the 3 and 4 positions. The combination of a nitrogen-rich ring and two vicinal amino groups makes this compound a highly valuable starting material for constructing fused heterocyclic systems. In the synthetic laboratory, vicinal diamines of this type are classic partners for condensation reactions with dicarbonyl compounds, allowing researchers to assemble new bicyclic frameworks directly. Its role is particularly prominent in advanced heterocyclic chemistry research and in the development of high-nitrogen-content materials.
The property that makes this compound a preferred choice lies in the electronic character of its furazan ring. The oxadiazole core is strongly electron-withdrawing, which lowers the basicity of both amino groups and gives a reactivity profile distinctly different from that of ordinary aromatic diamines such as o-phenylenediamine. This characteristic is exploited to tune the electronic properties of the synthesised molecules, for example in the design of ligands, dyes, and compounds with high nitrogen density. The furazan ring also contributes good thermal stability to many of the derivatives built from it, which is an advantage when the target structures must survive demanding reaction or processing conditions.
In Indonesian laboratories, this material is typically used in university and institutional research groups working on synthetic organic chemistry and heterocyclic chemistry, as well as in materials-oriented laboratories investigating nitrogen-rich structures. It is normally handled at the bench scale, in fume hoods, as part of multi-step synthetic routes where a defined heterocyclic building block is required. Supplied as a TCI catalogue reagent, it suits research and method-development work rather than routine production use.
Laboratory Applications
- Synthesis of fused heterocyclic systems: the two vicinal amino groups condense readily with dicarbonyl reagents, giving researchers direct access to new bicyclic frameworks from a single starting material.
- High-nitrogen-content materials research: the nitrogen-rich furazan core raises the overall nitrogen density of target molecules, making it a logical building block for laboratories studying such materials.
- Ligand design and coordination chemistry studies: the electron-withdrawing oxadiazole core lets chemists tune donor strength and electronic behaviour when preparing ligand scaffolds for further investigation.
- Dye and functional chromophore development: the compound's distinctive electronic character is used to adjust the electronic properties of synthesised molecules intended as dyes or related functional structures.
- Reactivity and structure–property investigations: its lowered amino-group basicity, compared with o-phenylenediamine, provides a useful reference point for teaching and studying substituent electronic effects in heterocycles.
Specifications
- Brand: TCI (Tokyo Chemical Industry)
- CAS number: 17220-38-1
- Catalogue number: D4030
- Chemical name: 3,4-Diaminofurazan (3,4-diamino-1,2,5-oxadiazole)
- Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
- Pack sizes: available in standard TCI research pack sizes; please confirm the currently listed options when ordering
- Storage: keep in a cool, dry place in the tightly closed original container
Handling and Storage
Store the material in a cool, dry, well-ventilated area, away from heat sources, direct sunlight, and incompatible chemicals, keeping the container tightly closed at all times. The original manufacturer container is the most suitable primary packaging; if transfer is necessary, use clean, dry, chemically compatible and clearly labelled containers. Handle the compound inside a fume hood and wear appropriate personal protective equipment, including safety goggles, gloves, and a laboratory coat. Avoid generating dust, and avoid inhalation or contact with skin and eyes. Always consult the manufacturer's Safety Data Sheet before use, and dispose of residues and contaminated materials in accordance with applicable laboratory chemical waste procedures.
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