• 1-(2-Furoyl)piperazine Hydrochloride (CAS 60548-09-6) - TCI F0705 - AMI Scientific
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TCI

CAS 60548-09-6

1-(2-Furoyl)piperazine Hydrochloride TCI F0705

1-(2-Furoyl)piperazine Hydrochloride TCI F0705
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Rp 1.004.850,00
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TCI F0705 1-(2-Furoyl)piperazine Hydrochloride is a heterocyclic compound that combines a piperazine ring with a furoyl group, an acyl derivative of the furan ring, and is supplied as the hydrochloride salt. The material serves as a heterocyclic building block in organic synthesis and medicinal chemistry laboratories. The piperazine ring is one of the most frequently encountered scaffolds in bioactive molecules, while the pre-installed furoyl group makes this compound a ready-to-use starting material for researchers constructing target molecules that require a specific substitution pattern on the piperazine nitrogen.

The key characteristic that makes this compound a preferred choice is that one piperazine nitrogen is already acylated while the other remains free for further reaction. This built-in protection pattern saves working steps, because researchers do not need to carry out selective acylation themselves, a step that on a symmetrical piperazine often produces a mixture of products. The hydrochloride salt form offers the practical advantage of a solid that is generally easier to handle, weigh, and store than the free base, and it helps maintain the stability of the material during storage and routine laboratory work.

In Indonesian laboratories, this building block is typically used in university research groups, pharmaceutical research and development units, and synthetic chemistry facilities that prepare piperazine-containing target molecules. It is drawn on when a synthetic route calls for a mono-acylated piperazine intermediate that can be taken forward through further functionalisation of the remaining free nitrogen, and it fits naturally into bench-scale exploratory and route-development work.

  • Heterocyclic building block synthesis: the compound provides a ready piperazine-furoyl framework so researchers can begin a synthetic route from an already assembled heterocyclic core rather than building it themselves.
  • Medicinal chemistry research: the piperazine ring is among the most common scaffolds in bioactive molecules, making this material useful for preparing candidate structures around a well-established pharmacophore fragment.
  • Selective functionalisation of piperazine nitrogen: one nitrogen is already acylated while the other stays free, allowing chemists to react a single defined position without the mixtures that symmetrical piperazines tend to give.
  • Preparation of substituted target molecules: the pre-installed furoyl group lets researchers pursue specific substitution patterns on the piperazine nitrogen without performing a separate selective acylation step first.
  • Organic synthesis intermediate work: supplied as a hydrochloride salt, the material is convenient to weigh and dispense during multi-step bench-scale route development and intermediate preparation.

Brand TCI
CAS number 60548-09-6
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes available in standard TCI catalogue pack sizes; please refer to the product listing for the options offered
Physical form solid, generally easier to handle and weigh than the corresponding free base
Storage keep in the tightly closed original container as supplied
  • Chemical form: hydrochloride salt of 1-(2-Furoyl)piperazine

Store the material in its tightly closed original container, kept in a cool, dry place away from moisture and direct sunlight, since the hydrochloride salt form is intended to help maintain the stability of the compound during storage. Suitable containers are the supplier's own sealed bottle or a clean, well-closed chemical container that is clearly labelled with the compound name and CAS number. Handle the solid in a well-ventilated area or fume hood, avoid the generation and inhalation of dust during weighing and transfer, and use standard laboratory personal protective equipment including gloves, safety glasses, and a laboratory coat. Close the container promptly after use, keep it separate from incompatible reagents, and consult the manufacturer's safety data sheet before handling.

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