6PPD-quinone: Tire-Derived Environmental Pollutant for HPLC Analysis and Toxicology Research
6PPD-quinone (P3373) is an environmental toxicant formed when 6PPD, an antioxidant widely used in automobile tires in urban areas, undergoes oxidation in the environment. It has been identified as acutely lethal to coho salmon (Oncorhynchus kisutch).¹) Recent studies report that even low concentrations of 6PPD-quinone in urban runoff can cause sudden death in salmon.²) ³) The product is supplied as a chemically synthesized substance, ensuring reproducibility and reliability of experimental data, and is highly suitable for HPLC analysis and calibration curve preparation. Its applications include environmental risk assessment and control, as well as environmental toxicology research. Long-term risks, such as potential effects on non-target organisms through the food chain, are also of concern.
Related products
- TCI P3373 2754428-18-5 2-[(4-Methylpentan-2-yl)amino]-5-(phenylamino)cyclohexa-2,5-diene-1,4-dione
- TCI D3331 793-24-8 N-(1,3-Dimethylbutyl)-N'-phenyl-1,4-phenylenediamine
References
- Z. Tian, E. P. Kolodziej, et al., Science 2021, 371, 185. doi:10.1126/science.abd6951
- Z. Tian, E. P. Kolodziej, et al., Environ. Sci. Technol. Lett. 2022, 9, 140. doi:10.1021/acs.estlett.1c00910
- K. Hiki, H. Yamamoto, et al., Environ. Sci. Technol. Lett. 2021, 8, 779. doi:10.1021/acs.estlett.1c00453
Download TCI brochure Tire-Derived Environmental Pollutant 6PPD-quinone (PDF)
Source
- TCI Product Highlights: www.tcichemicals.com/ID/en/product/tci-topics/ProductHighlights_20251013
- TCI product page P3373: tcichemicals.com/ID/en/p/P3373
- TCI brochure AA015: Tire-Derived Environmental Pollutant 6PPD-quinone
For research and laboratory use only, not for human consumption.
