Capsule-Form Condensing Agent for Condensation Reactions (DMT-MM)
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Reagents for Condensation Reactions (HPMC encapsulated) (DMT-MM) [R0294] is a capsule form of DMT-MM, a condensing agent for condensation reactions. Each capsule contains 0.30 mmol of DMT-MM, so the reagent can eliminate the need for weighing. The capsule is made of water-soluble HPMC (hydroxypropyl methylcellulose), and the HPMC is removed during aqueous workup with saturated sodium sulfate solution. In the example, one capsule was added to 4-bromobenzoic acid (0.30 mmol) and morpholine (1.05 eq.) in methanol at room temperature, then stirred at 30 °C for 24 hours and monitored by UPLC. After purification by silica gel chromatography, (4-bromophenyl)(morpholino)methanone was obtained in 86% yield as a white solid.
Related products
- TCI B0553 586-76-5 4-Bromobenzoic Acid
- TCI M0465 110-91-8 Morpholine
- TCI D2919 3945-69-5 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium Chloride
References
- HPMC: A Biomass-Based Semisynthetic Sustainable Additive Enabling Clean and Fast Chemistry in WaterS. Sharma, T. N. Ansari, S. Handa, ACS Sustainable Chem. Eng. 2021, 9, 12719.<< PrevNext >>Page Top
Source
- TCI Practical Example: www.tcichemicals.com/ID/en/product/tci-topics/TCIPracticalExample_20241118
- TCI product page B0553: tcichemicals.com/ID/en/p/B0553
For research and laboratory use only, not for human consumption.
