Catechol-Containing Methacrylate Monomer for Biomimetic Adhesives
3,4-Dihydroxyphenethyl methacrylate (D6660) is a catechol-containing methacrylate monomer used for synthesizing biomimetic materials. Mussels adhere to rocks and other surfaces in the sea using a catechol-containing protein called mussel adhesive protein, and numerous adhesives mimicking this function have been reported for medical and underwater applications.³) Polymers obtained from D6660 show excellent adhesion in water and low toxicity, and the adhesive prepared from this monomer with co-monomer M0591 is suited to applications requiring high bonding strength.²) The bonding strength of adhesives using D6660 is comparable to that of adhesives using N-(3,4-Dihydroxyphenethyl)methacrylamide (D5907), which has been used to introduce the catechol moiety. Because D6660 possesses ester bonds, improved biodegradability can be expected. For underwater use, D5907 with co-monomer M2282 enables repeatedly re-bondable adhesives.¹)
Related products
- TCI D5907 471915-89-6 N-(3,4-Dihydroxyphenethyl)methacrylamide
- TCI D6660 861243-34-7 3,4-Dihydroxyphenethyl Methacrylate (stabilized with MEHQ)
- TCI M2282 6976-93-8 2-Methoxyethyl Methacrylate (stabilized with MEHQ)
- TCI M0591 688-84-6 2-Ethylhexyl Methacrylate (stabilized with MEHQ)
References
- Y. Zhao et al., Nat. Commun. 2017, 8, 2218. doi:10.1038/s41467-017-02387-2
- T. Fujita et al., ACS Appl. Polym. Mater. 2023, 5, 3230. doi:10.1021/acsapm.3c00365
- P. Huang et al., Adv. Mater. 2025, in published. doi:10.1002/adma.202501542
- D. Gupta et al., RSC Appl. Polym. 2025, 3, 1145. doi:10.1039/D5LP00173K
- Y. Chen et al., ACS Macro Lett. 2018, 7, 904. doi:10.1021/acsmacrolett.8b00434
Download TCI brochure Catechol-Containing Monomers for the Development of Biomimetic Materials (PDF)
Source
- TCI Product Highlights: www.tcichemicals.com/ID/en/product/tci-topics/ProductHighlights_20251208
- TCI product page D5907: tcichemicals.com/ID/en/p/D5907
- TCI product page D6660: tcichemicals.com/ID/en/p/D6660
- TCI brochure FF222: Catechol-Containing Monomers for the Development of Biomimetic Materials
For research and laboratory use only, not for human consumption.
