1-(3-Fluorophenyl)-1H-pyrazole-4-carbaldehyde (CAS 936940-82-8) is a heterocyclic building block in which a pyrazole ring carries both a 3-fluorophenyl substituent and an aldehyde group. Supplied by Ossila at 98% purity as a brown powder or crystals, it serves as a reaction intermediate in the preparation of active pharmaceutical ingredients.
Pyrazole-based structures appear in a range of APIs, celecoxib among them. This aldehyde is a starting point for LQFM021, an anti-inflammatory pyrazole candidate, made in two steps: the aldehyde is first converted into a nitrile, and a tetrazole ring is then built using sodium azide.
The compound has also been used to prepare a disubstituted urea based on the pyrazole scaffold, studied as an anti-melanoma agent. With several functional groups available for further reactions, it suits drug discovery, medicinal chemistry and biochemistry research.
- Intermediate in the synthesis of active pharmaceutical ingredients based on pyrazole scaffolds.
- Precursor to the anti-inflammatory pyrazole compound LQFM021 via nitrile and tetrazole formation.
- Building block for pyrazole-based disubstituted ureas investigated as anti-melanoma agents.
- Fluorinated heterocyclic aldehyde for drug discovery and medicinal chemistry research.
| Brand | Ossila |
|---|---|
| CAS number | 936940-82-8 |
| Molecular formula | C10H7FN2O |
| Purity | 98% |
| Category | — |
| Pack sizes | 1 g, 2 g |
| Physical form | Brown powder/crystals |
| Storage | — |
- Product code: B2951
- Product Code: B2951
- Molecular Weight: 190.17 g/mol
- Classification / Family: Fluorinated building blocks, Heterocyclic building blocks, Aldehyde building blocks, APIs
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