2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile (CAS 82671-02-1) from Ossila is a halogenated pyridine bearing two chlorine atoms, one fluorine atom and a nitrile group. Also known as 2,6-dichloro-3-cyano-5-fluoropyridine or 2,6-dichloro-5-fluoronicotinonitrile, it serves as a fluorinated nicotinonitrile building block for preparing active pharmaceutical ingredients (APIs).
Its best-known use is as a precursor to Gemifloxacin, an orally administered broad-spectrum antibiotic. The compound also acts as a scaffold for other 1,8-naphthyridine derivatives, including Enoxacin, Trovafloxacin and Tosufloxacin. Because it carries several reactive functional groups, it can be combined with a variety of building blocks to make new fluoroquinolone derivatives, an approach explored for lowering drug side effects and widening medical uses.
The material is a white powder with a purity above 98% and a melting point of 89 °C – 91 °C, suited to organic synthesis, medicinal chemistry and biochemistry research.
- Synthesis of the broad-spectrum antibiotic Gemifloxacin and its derivatives.
- Preparation of 1,8-naphthyridine antibiotics such as Enoxacin, Trovafloxacin and Tosufloxacin.
- Development of new fluoroquinolone derivatives in medicinal chemistry research.
- Use as a fluorinated heterocyclic building block in general organic synthesis.
- Research on naphthyridinone derivatives for antitumor activity studies.
| Brand | Ossila |
|---|---|
| CAS number | 82671-02-1 |
| Molecular formula | C6HCl2FN2 |
| Purity | >98% |
| Category | — |
| Pack sizes | 25 g, 50 g |
| Physical form | White powder |
| Storage | — |
- Product code: B2541
- Molecular Weight: 190.99 g/mol
- Synonyms: 2,6-Dichloro-3-cyano-5-fluoropyridine, 2,6-Dichloro-5-fluoro-3-nicotinonitrile, 2,6-Dichloro-5-fluoronicotinonitrile
- Classification / Family: Fluorinated building blocks, Heterocyclic building blocks, APIs, Antibiotics, Bicyclic compounds
- Melting Point: 89 °C – 91 °C
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