3,3-Difluoroazetidine hydrochloride (CAS 288315-03-7) is a fluorinated heterocyclic building block based on azetidine, a four-membered ring made up of three carbon atoms and one nitrogen atom. Supplied as a white powder with a purity above 97% (1H NMR), it serves as a precursor in the synthesis of fluorescent dyes and energetic materials.
The pair of fluorine atoms at the 3-position raises the lipophilicity of the molecule, which helps with solvent processability. Azetidine's ring strain (27.7 Kcal/mol) makes the nitrogen lone pair more accessible, so the compound acts as a stronger nucleophile and reacts faster than other secondary amines.
In bioimaging research, it is incorporated into rhodamine dyes to fine-tune their fluorescence wavelengths. Because it can adjust the HOMO-LUMO energy gap, it also shows promise for OLED and dye-sensitized solar cell (DSSC) materials. It is further used to build triazolyl polycyclic energetic materials with improved stability and density.
- Precursor for rhodamine dyes with tuned fluorescence wavelengths for bioimaging.
- Building block for tuning HOMO-LUMO energy gaps in OLED materials.
- Precursor for dyes in dye-sensitized solar cells (DSSCs).
- Synthesis of triazolyl polycyclic energetic materials with improved stability and density for combustion applications.
| Brand | Ossila |
|---|---|
| CAS number | 288315-03-7 |
| Molecular formula | C3H6F2NCl |
| Purity | >97% (1H NMR) |
| Category | — |
| Pack sizes | 5 g |
| Physical form | White powder |
| Storage | — |
- Product code: B1561
- Molecular Weight: 129.54 g/mol
- Melting Point: 136 °C – 140 °C
- Classification / Family: Azetidine derivatives, Fluorinated building blocks, Heterocyclic building block, Dyes
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