3,5-Difluorobenzonitrile (CAS 64248-63-1, C7H3F2N) is a benzonitrile derivative carrying fluorine atoms at both meta positions. Supplied by Ossila as a white powder with >98% purity, it serves as a fluorinated building block for organic synthesis, drug discovery and OLED research.
In optoelectronics, the molecule acts as an electron-accepting unit in axially chiral excimers and exciplexes that emit cyan light and show thermally activated delayed fluorescence (TADF). Its chromophore can be extended by attaching carbazole derivatives via nucleophilic aromatic substitution; emitters built this way have reached a photoluminescence quantum yield (PLQY) of 29% and an external quantum efficiency (EQE) of 5.3%.
The compound is also relevant to organometallic chemistry, where it helps convert catalytically inactive (phosphine)2Ni into (phosphine)Ni(alkene), an intermediate sought in cross-coupling catalysis.
- Electron acceptor unit in TADF emitters and chiral exciplexes for OLED research.
- Synthesis of carbazole-substituted emitters through nucleophilic aromatic substitution.
- Generation of (phosphine)Ni(alkene) catalyst intermediates for cross-coupling reactions.
- Fluorinated building block for drug discovery and general organic synthesis.
| Brand | Ossila |
|---|---|
| CAS number | 64248-63-1 |
| Molecular formula | C7H3F2N |
| Purity | >98% |
| Category | — |
| Pack sizes | 10 g, 25 g, 50 g |
| Physical form | White powder |
| Storage | — |
- Product code: B2431
- Molecular Weight: 139.10 g/mol
- Synonyms: 5-Cyano-1,3-difluorobenzene
- Melting Point: 84 °C – 86 °C
- Classification / Family: Fluorinated building block, Benzonitrile derivatives, Dyes, OLEDs, Ligands, Catalysts
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