Ossila 4-(1,2,2-Triphenylvinyl)benzaldehyde B3881

4-(1,2,2-Triphenylvinyl)benzaldehyde (TPVBA, also known as TPE-CHO) from Ossila is a tetraphenylethylene building block with CAS number 1289218-74-1 and a purity above 98%. Its tetraphenylethylene (TPE) core carries a single aldehyde group at the 4-position of one phenyl ring, making it a formyl linker for covalent organic frameworks (COFs) and covalent polymeric frameworks, where it can serve to end-cap the network.

Because the TPE unit shows aggregation-induced emission (AIE), this aldehyde is used to build luminescent materials. In one reported route, a one-pot reaction with carboxyl methyl starch sodium and amino phenylboronic acid gave TPE-CMS luminescent polymeric nanoprobes with good water dispersibility, biocompatibility and efficient uptake into cells.

A derived quinolinium salt, TPE-QN, gives strong red emission in water that is quenched by iodide, enabling iodide sensing with a detection limit of 22.6 nM and secondary detection of Hg2+ down to 71.8 nM. The aldehyde group offers excellent reactivity for straightforward reactions. The compound is supplied as a white to off-white to yellow powder or crystals in 1 g and 5 g packs.

• Aldehyde linker and end-capping ligand for covalent organic frameworks and covalent polymeric frameworks.
• Building block for aggregation-induced emission (AIE) luminescent materials.
• Preparation of starch-based luminescent polymeric nanoprobes for biological imaging.
• Synthesis of fluorescent sensors for iodide and mercury ions in aqueous solution.
• Development of tetraphenylethene-based emitters for non-doped blue OLEDs.

• Product code: B3881
• Full Name: 4-(Triphenylvinyl)benzaldehyde
• M​olecular Weight: 360.45 g/mol
• Synonyms: TPVBA, TPE-CHO, 1-(4-Formylphenyl)-1,2,2-triphenylethene
• Family: tetraphenylethylenes, Carbaldehydes, COFs
• Melting Point: 151 °C

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