4-Fluoro-1,2-phenylenediamine (CAS 367-31-7) is an ortho-phenylenediamine carrying a fluorine substituent, supplied by Ossila as a brown powder with purity above 97%. Its two neighbouring amine groups make it a versatile building block for drug discovery, ligand design, materials and battery research.
Because the amines sit in the ortho position, the compound condenses with salicylaldehydes to give salen-type Schiff bases. These ligands bind Co, Ni, Cu and Zn to form metal complexes that have been explored as antimicrobial agents and as redox carriers in flow batteries. Oxidative reaction of the diamine also gives access to 2,3-diaminophenazines, a class of compounds used in dyes and in drug discovery.
Outside synthesis, the diamine acts as an amine hardener for epoxy resins, where it raises the thermal conductivity of the cured material and helps with heat management in electrical motors and integrated circuits.
- Preparation of salen-type Schiff base ligands by condensation with salicylaldehydes.
- Synthesis of Co, Ni, Cu and Zn Schiff base complexes studied as antimicrobial agents.
- Development of Schiff base metal complexes as redox carriers for flow batteries.
- Oxidative synthesis of 2,3-diaminophenazines for dyes and drug discovery.
- Use as an epoxy resin hardener to improve thermal conductivity for thermal management of electrical motors and integrated circuits.
| Brand | Ossila |
|---|---|
| CAS number | 367-31-7 |
| Molecular formula | C6H7FN2 |
| Purity | >97% |
| Category | — |
| Pack sizes | 5 g, 10 g, 25 g, 50 g |
| Physical form | Brown powder |
| Storage | — |
- Product code: B3431
- Full Name: 4-Fluoro-1,2-benzenediamine
- Molecular Weight: 126.13 g/mol
- Synonyms: 3,4-Diamino-1-fluorobenzene, 2-Amino-4-fluoroaniline, 4-Fluoro-o-phenylenediamine
- Melting Point: 94 °C – 98 °C
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