4-(Trifluoromethyl)-2-pyridone (CAS 50650-59-4) is a fluorinated pyridone building block supplied as a white powder with >98% purity (1H NMR). It serves as a starting material for key intermediates in pharmaceutical production and drug discovery research.
The molecule combines a 2-pyridone core with a trifluoromethyl group at the 4-position of the ring. Trifluoromethyl is regarded as one of the strongest electron-withdrawing groups, which makes this pyridone highly electron deficient. The compound exists in tautomeric forms, so it is also known as 2-hydroxy-4-(trifluoromethyl)pyridine, and like other 2-pyridones it can form dimers through hydrogen bonding.
With several functional groups available for reaction, it supports straightforward synthetic routes. It is classed among pyridone derivatives, semiconductor synthesis intermediates and photocatalyst materials, with a molecular weight of 163.10 g/mol and a melting point of 158 °C.
- Building block for synthesising key intermediates in pharmaceutical production.
- Starting material in drug discovery and medicinal chemistry programmes.
- Intermediate in the synthesis of semiconductor materials.
- Precursor for photocatalyst development.
| Brand | Ossila |
|---|---|
| CAS number | 50650-59-4 |
| Molecular formula | C6H4F3NO |
| Purity | >98% (1H NMR) |
| Category | — |
| Pack sizes | 1 g, 5 g, 10 g |
| Physical form | White powder |
| Storage | — |
- Product code: B1481
- Molecular Weight: 163.10 g/mol
- Synonyms: 2-Hydroxy-4-(trifluoromethyl)pyridine, 4-(Trifluoromethyl)pyridin-2-ol
- Classification / Family: Pyridone derivatives, Semiconductor synthesis intermediates, Organometallic compounds, Photocatalyst
- Melting Point: 158 °C
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