5-(4-(Diphenylamino)phenyl)thiophene-2-carbaldehyde, also known as DPAPTA (CAS 291279-14-6), is a triphenylamine-based aldehyde building block used as a ligand linker for covalent organic frameworks (COFs) and as a precursor for aggregation induced emission (AIE) materials. One phenyl ring of its triphenylamine core carries a 2-carbaldehydethiophene unit.
The formyl group reacts readily with amines in condensation reactions, creating double-bond π-bridges, and it can also serve to end-cap COF networks. Supplied at >98% purity as a yellow to orange powder or crystals.
Compounds derived from DPAPTA have been reported in the literature as AIE two-photon fluorescent probes for brain vasculature imaging, mitochondria-targeting photosensitizers that generate reactive oxygen species under visible light, colorimetric and fluorescent probes for cyanide ions, and water-soluble near-infrared AIEgens for wash-free cell membrane staining.
- Aldehyde ligand linker and end-capping unit for covalent organic framework (COF) synthesis.
- Building block for AIE two-photon fluorescent probes used in brain vasculature imaging.
- Precursor for mitochondria-anchoring AIE photosensitizers studied for cholangiocarcinoma cell ablation.
- Synthesis of triphenylamine-thiophene fluorescent probes for cyanide ion detection.
- Preparation of water-soluble NIR AIEgens for wash-free cell membrane imaging.
| Brand | Ossila |
|---|---|
| CAS number | 291279-14-6 |
| Molecular formula | C23H17NOS |
| Purity | >98% |
| Category | — |
| Pack sizes | 1 g, 5 g |
| Physical form | Yellow to orange powder/crystals |
| Storage | — |
- Product code: B3811
- Molecular Weight: 355.45 g/mol
- Synonyms: DPAPTA, 2-Thiophenecarboxaldehyde, 5-[4-(diphenylamino)phenyl]-
- Classification / Family: Triphenylamine, COF ligands, Aggregation induced emission (AIE)
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