5-Bromo-3-fluorosalicylaldehyde (CAS 251300-28-4), also named 5-bromo-3-fluoro-2-hydroxybenzaldehyde, is a fluorinated salicylaldehyde derivative supplied by Ossila at >97% purity as a yellow powder. Bromo and fluoro substituents sit on the benzene ring alongside the hydroxyl and aldehyde groups, making it a versatile multifunctional building block.
Its main role is as a precursor to Schiff bases, a sub-class of imines. Reacting the aldehyde with an aliphatic or aryl amine gives a hemiaminal through nucleophilic addition, which then loses water to yield the aldimine.
The resulting Schiff bases act as bidentate or tetradentate ligands that can coordinate to metals. These complexes serve as dyes in OLEDs and dye-sensitized solar cells, with DSSC power conversion efficiency reported at circa 7.7 %, and are also studied for antimicrobial activity against bacteria and fungi.
- Starting material for synthesizing Schiff base ligands via condensation with amines.
- Preparation of metal coordination complexes used as emissive dyes in OLEDs.
- Synthesis of dyes for dye-sensitized solar cells (DSSCs).
- Research into Schiff base complexes with antimicrobial activity against bacteria and fungi.
- Intermediate for semiconductor materials in OFETs and organic photovoltaics.
| Brand | Ossila |
|---|---|
| CAS number | 251300-28-4 |
| Molecular formula | C7H4BrFO2 |
| Purity | >97% |
| Category | — |
| Pack sizes | 2 g, 5 g, 10 g |
| Physical form | Yellow powder |
| Storage | — |
- Product code: B1831
- Full Name: 5-bromo-3-fluoro-2-hydroxybenzaldehyde
- Molecular Weight: 219.01 g/mol
- Melting Point: 112 °C – 116 °C
- Classification / Family: Fluorinated building block, Schiff base, Dyes, Semiconductor synthesis intermediates, OLED, OFETs, organic photovoltaics
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