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CAS 2230958-14-0

(S,R,S)-AHPC Hydrochloride TCI A3412

(S,R,S)-AHPC Hydrochloride TCI A3412

Chemical Identity

CAS No.
2230958-14-0
PubChem
CID 89702519·SID 468590286
Formula
C22H30N4O3S
Molecular weight
430.6 g/mol
Purity
>98.0%(HPLC)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2S,4R)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
SMILES
CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)N)O
InChIKey
ZLOXMSNKPDWMEF-ZIFCJYIRSA-N
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(3 paragraphs. Paragraph 1 AT LEAST 70 words: what this material/instrument is and its role in the laboratory. Paragraph 2 AT LEAST 70 words: the properties that make it a preferred choice. Paragraph 3 AT LEAST 60 words: typical use context in Indonesian laboratories.)

The TCI A3412 2230958-14-0 (S,R,S)-AHPC Hydrochloride is a chemical compound used in pharmaceutical research and development. It plays a crucial role in the study of proteolysis targeting chimera (PROTAC) technology, which is a promising approach in drug discovery. This compound is essential for researchers aiming to develop novel therapeutics by selectively targeting and degrading disease-related proteins. Its application spans across various biochemical and pharmacological studies, making it a valuable tool for scientists working in drug discovery and development.

This compound is preferred due to its high purity and chemical stability, which ensures consistent results in experimental settings. Its hydrochloride salt form enhances solubility, making it easier to handle in aqueous solutions. Additionally, its well-defined molecular structure allows for precise experimental design and reproducibility. These characteristics make it a reliable choice for laboratories conducting advanced research in proteolysis and enzyme specificity.

In Indonesian laboratories, this compound is commonly used in academic and industrial research settings. It supports the development of new drugs and therapeutic strategies, particularly in the field of pharmacology and biotechnology. Its application is widespread in both public and private research institutions, contributing to the advancement of scientific knowledge and innovation in the region.

  • Used in proteolysis targeting chimera (PROTAC) research for developing novel drug candidates that selectively degrade target proteins.
  • Applied in enzyme specificity studies to evaluate the interaction between proteins and enzymatic activity in biochemical pathways.
  • Employed in pharmaceutical development for assessing the biological activity of potential therapeutic agents.
  • Utilized in structural biology research to understand protein conformation and function in drug-target interactions.
  • Integrated into drug discovery workflows for screening and validation of compounds with therapeutic potential.

From the TCI brochure

  • Ubiquitin ligase ligand for synthesis of proteolysis targeting compounds

Brand TCI
CAS number 2230958-14-0
Molecular formula —
Purity —
Category Chemistry > Pharmaceutical Development and Drug Discovery Research Reagents > Proteolysis Targeting Chimera Research Reagents
Pack sizes Available in various quantities as per supplier specifications
Physical form Solid powder
Storage Store in a cool, dry place away from moisture and direct sunlight

This compound should be stored in a cool, dry environment to maintain its chemical integrity and prevent degradation. It is recommended to use airtight containers to protect it from moisture and contaminants. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles. Avoid exposure to direct sunlight and ensure proper ventilation in the laboratory. Regular monitoring of storage conditions is advised to ensure the material remains suitable for use in research applications.

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