5-Bromouridine TCI B0666

Chemical Identity

CAS No.: 957-75-5
PubChem: CID 91494·SID 87563672
Formula: C9H11BrN2O6
Molecular weight: 323.10 g/mol
Purity: >99.0%(HPLC)
Reference databases: ChEBI·ChemSpider·ECHA·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 5-bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
SMILES: C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)Br
InChIKey: AGFIRQJZCNVMCW-UAKXSSHOSA-N

Rp 557.550,00

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Berat 100mg 1g

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5-Bromouridine is a chemical compound classified under the category of nucleosides. It plays a crucial role in biochemical and molecular biology research, particularly in the study of RNA transcription and DNA replication mechanisms. In the laboratory, it is widely used as a substitute for uridine in RNA synthesis due to its ability to bind to RNA polymerase and produce more stable RNA molecules. This compound is essential for researchers aiming to explore molecular interactions and genetic functions.

The unique chemical structure of 5-Bromouridine, which closely resembles uridine but with a bromine atom at the 5-position, gives it distinct properties that make it a preferred choice in various experimental settings. Its stability and controlled reactivity allow it to be used in diverse applications such as RNA mutation studies, enzyme activity testing, and research on the effects of nucleoside modifications on gene function. These characteristics make it a reliable and versatile reagent for scientific investigations.

In Indonesian laboratories, 5-Bromouridine is commonly utilized by researchers in universities and research centers. It is an essential tool for those working on molecular biology, biochemistry, and virology projects. Its availability and reliability make it a standard component in many laboratory workflows, supporting both basic and applied research efforts.

TCI brochures (PDF)

Nucleosides, Nucleotides, Nucleic Acids and Related Reagents 2026-03-23 · p. 3

Related TCI products

RNA synthesis and modification studies benefit from 5-Bromouridine due to its ability to bind RNA polymerase and produce stable RNA.
Enzyme activity assays use this compound to test the specificity and efficiency of RNA polymerase and other nucleotide-processing enzymes.
Molecular biology research leverages its structural similarity to uridine for studying RNA structure and function in genetic processes.
Antiviral research utilizes its potential therapeutic applications in the development of new pharmaceutical compounds.
Genetic function studies explore how nucleoside modifications affect gene expression and cellular processes.

Brand	TCI
CAS number	957-75-5
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Nucleosides, Nucleotides, Oligonucleotides
Pack sizes	Available in various quantities as per standard laboratory supply options
Physical form	Solid powder
Storage	Store in a cool, dry place away from light and moisture

5-Bromouridine should be stored in a cool, dry place away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Laboratory personnel should handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. Proper ventilation should be ensured when working with this material to minimize inhalation risks. The compound is non-hazardous under normal conditions but should be treated as a chemical reagent requiring standard laboratory safety protocols. Regular monitoring of storage conditions ensures the integrity and usability of the material for research purposes.

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