1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene TCI B2436

Chemical Identity

Other names: Me-DUPHOS · (R,R)-Me-DUPHOS
CAS No.: 147253-67-6
PubChem: CID 2734551·SID 468590490
Formula: C18H28P2
Molecular weight: 306.4 g/mol
Purity: >98.0%(GC)
Reference databases: ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (2R,5R)-1-[2-[(2R,5R)-2,5-dimethylphospholan-1-yl]phenyl]-2,5-dimethylphospholane
SMILES: C[C@@H]1CC[C@H](P1C2=CC=CC=C2P3[C@@H](CC[C@H]3C)C)C
InChIKey: AJNZWRKTWQLAJK-KLHDSHLOSA-N

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TCI B2436, also known as 1,2-Bis[(2R,5R)-2,5-dimethylphospholano]benzene, is a specialized chemical compound used in asymmetric synthesis to produce chiral molecules with precise stereochemical structures. This compound functions as a chiral ligand or catalyst in chemical reactions requiring strict stereoselectivity control. Its unique molecular structure enables it to interact specifically with substrates, enhancing reaction efficiency and selectivity. In laboratory settings, it is a valuable tool for researchers working on complex organic transformations and pharmaceutical development.

The compound’s effectiveness stems from its complex molecular architecture and its ability to act as a chiral reagent. The presence of multiple stereocenters in its structure allows for high stereoselectivity in asymmetric reactions. This makes it a preferred choice for applications where precise control over the stereochemistry of the final product is essential. Its stability and compatibility with various reaction conditions further contribute to its reliability in synthetic processes.

In Indonesian laboratories, this compound is widely used in scientific research and pharmaceutical development. Researchers and scientists rely on it to synthesize bioactive compounds with specific structures, which are crucial for drug discovery and development. Its role in asymmetric synthesis makes it an essential component in studies focused on chiral molecule production and advanced organic chemistry applications.

TCI brochures (PDF)

Chiral Ligands 2024-12-13 · p. 1
Asymmetric Synthesis 2026-03-18 · p. 4
Ligands 2025-12-01 · p. 2

Related TCI products

Asymmetric synthesis applications benefit from its chiral structure, enabling precise control over stereochemical outcomes in complex reactions.
Pharmaceutical research utilizes this compound to develop bioactive molecules with specific stereochemistry, enhancing drug efficacy and selectivity.
Organic chemistry experiments rely on its catalytic properties to achieve high stereoselectivity in synthetic pathways.
Chiral ligand studies use it to investigate interaction mechanisms with substrates, improving reaction efficiency and yield.
Drug development projects incorporate it to synthesize chiral compounds with desired biological activities and molecular configurations.

Brand	TCI
CAS number	147253-67-6
Molecular formula	—
Purity	—
Category	Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents
Pack sizes	—
Physical form	—
Storage	Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical integrity. It is recommended to use airtight containers made of materials compatible with its chemical nature to prevent contamination and degradation. In laboratory settings, proper ventilation should be ensured when handling the compound to minimize exposure. Due to its chiral nature and potential reactivity, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. Storage conditions should be consistent to avoid any changes in its physical or chemical properties that could affect its performance in synthetic reactions.

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