TCI B6362, Boc-Arg-OH (CAS 13726-76-6), is an Nα-Boc-protected arginine derivative intended for peptide chemistry applications. The tert-butoxycarbonyl group masks the α-amino function so that coupling reactions proceed selectively, and it can subsequently be removed under acidic conditions within a Boc-based synthetic strategy. Arginine residues contribute the guanidine side chain that underpins molecular recognition, charge-driven interactions, and the design of cell-penetrating peptides. AMI Scientific offers this TCI reagent in 1 g and 5 g pack sizes for solid-phase and solution-phase peptide synthesis in research laboratories.
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- Imaizumi et al. (2000). Anterograde axonal transport of Boc-Arg-Val-Arg-Arg-MCA hydrolyzing enzyme in rat sciatic nerves: cleavage occurs between basic residues. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology doi:10.1016/s0167-4838(99)00239-3
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