• Z-Asp(OtBu)-OH (CAS 5545-52-8) - TCI B6364 - AMI Scientific
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TCI

CAS 5545-52-8

Z-Asp(OtBu)-OH TCI B6364

Z-Asp(OtBu)-OH TCI B6364
Rp 1.167.600,00
Rp 1.167.600,00
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TCI B6364, Z-Asp(OtBu)-OH (CAS 5545-52-8), is a doubly protected aspartic acid derivative bearing a benzyloxycarbonyl group on the amino function and a tert-butyl ester on the side-chain carboxyl. This orthogonal arrangement lets chemists remove each protecting group under different conditions — hydrogenolysis for the Z group and acid for the tert-butyl ester — giving precise control over each synthetic step. Keeping the side chain masked helps suppress unwanted cyclisation and branching at aspartate residues during chain elongation. AMI Scientific supplies this TCI peptide-chemistry reagent in 5 g and 25 g pack sizes for research use.

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  • Kates et al. (1995). Rearrangement of Glu(OtBu)- and Asp(OtBu)-containing peptides upon fluoride treatment in solid-phase synthesis. Letters in Peptide Science doi:10.1007/bf00127267
  • Hamzé dkk. (2003). Synthesis of (R) and (S) enantiomers of Fmoc-protected 1,2,4-oxadiazole-containing β3-amino acids from Fmoc-(R)-β-HAsp(OtBu)-OH. Tetrahedron Letters doi:10.1016/s0040-4039(03)01471-0

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.

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