TCI
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Description
TCI B6509 6-Bromoquinazoline (CAS 89892-21-7) is a brominated quinazoline building block for heterocyclic and medicinal chemistry. The aryl bromide serves as a reliable handle for palladium-catalysed cross-coupling and related substitution chemistry. Its nitrogen-rich core is a frequently studied scaffold in the design of bioactive molecules and analogue libraries. Supplied as a 500 mg research pack, it should be handled with standard protective equipment and stored cool, dry, and protected from light.
Scientific References
- Zare et al. (2023). 6‐Bromoquinazoline Derivatives as Potent Anticancer Agents: Synthesis, Cytotoxic Evaluation, and Computational Studies. Chemistry & Biodiversity doi:10.1002/cbdv.202201245
- Głowacka et al. (2025). Design, synthesis and biological evaluation of a novel series of conjugates of N1-(phosphonoalkyl)-1,2,3-triazoles and N3-benzyl-6-bromoquinazoline-2,4-diones with anti-RSV activity. Antiviral Research doi:10.1016/j.antiviral.2025.106303
- Sadeghian et al. (2025). Synthesis, cytotoxic evaluation, molecular docking studies and molecular dynamic simulations of a new series of thio-6-bromoquinazoline-4(3H)-one derivatives. Results in Chemistry doi:10.1016/j.rechem.2025.102528
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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