BI-D 1870 TCI B6803

Chemical Identity

Other names: 2-[(3,5-Difluoro-4-hydroxyphenyl)amino]-8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6(5H)-one
CAS No.: 501437-28-1
Formula: C19H23F2N5O2
Molecular weight: 391.42 g/mol
Purity: >93.0%(HPLC)(qNMR)
Storage: 0-10°C

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 2-(3,5-difluoro-4-hydroxyanilino)-5,7-dimethyl-8-(3-methylbutyl)-7H-pteridin-6-one
SMILES: CC1C(=O)N(C2=CN=C(N=C2N1CCC(C)C)NC3=CC(=C(C(=C3)F)O)F)C
InChIKey: DTEKTGDVSARYDS-UHFFFAOYSA-N
MDL: MDL11223662
PubChem: CID 25023738

Rp 2.411.850,00

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TCI B6803 BI-D 1870 (CAS 501437-28-1) is a widely used small-molecule inhibitor of p90 ribosomal S6 kinase (RSK), acting on the N-terminal kinase domain. It serves as a standard pharmacological tool for dissecting the RAS–ERK–RSK axis in cell signalling and neuroscience research. Typical workflows involve preparing a DMSO stock solution, diluting into culture medium, and monitoring downstream substrate phosphorylation, proliferation, or translational output. Available in 5 mg and 25 mg packs, the compound should be stored cold, protected from light and moisture, and aliquoted to avoid repeated freeze–thaw cycles.

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(1991). Pawnee passage, 1870-1875. Choice Reviews Online doi:10.5860/choice.28-5271
(1991). Making America corporate, 1870-1920. Choice Reviews Online doi:10.5860/choice.28-3970
(1991). The Symbolist generation, 1870-1910. Choice Reviews Online doi:10.5860/choice.28-5510

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.