TCI C0561 2-Chlorobenzaldehyde (CAS 89-98-5) is an ortho-substituted aromatic aldehyde supplied as a non-heterocyclic building block for organic synthesis. Its aldehyde group readily undergoes Schiff base formation, Knoevenagel and aldol condensations, and selective reduction or oxidation, while the ring chlorine allows further functionalisation through substitution or metal-catalysed coupling. This dual reactivity makes it a common starting material for quinoline and imidazole scaffolds as well as pharmaceutical and agrochemical intermediates. Handle it in a fume hood with gloves and eye protection, and keep the container tightly closed in a cool, dark place to limit air oxidation.
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- S Satheeshkumar (2025). Group Theoretical Vibrational Analysis of 4-Chlorobenzaldehyde. International Journal of Science and Research (IJSR) doi:10.21275/sr251203184033
- Srivastava et al. (2025). Unveiling the synergistic catalytic potential of sodium lauryl sulfate micelles and Ag(I): insights into the Mn(VII)-directed p-chlorobenzaldehyde oxidation kinetics. Bulletin of the Chemical Society of Japan doi:10.1093/bulcsj/uoaf066
- Balcioǧlu et al. (1998). Advanced oxidation of 4-chlorobenzaldehyde in water by UV-light, ozonation and combination of both methods. Chemosphere doi:10.1016/s0045-6535(97)10084-4
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