TCI C0914 4-Chlorophenylacetic Acid (CAS 1878-66-6) is a para-chlorinated arylacetic acid widely used as a synthetic building block. Its carboxyl group is readily converted into esters, amides, acid chlorides, or alcohols, while the benzylic alpha carbon allows further alkylation. These features make the compound a common intermediate in medicinal chemistry routes and in the preparation of more elaborate aromatic frameworks. AMI Scientific supplies this TCI product in small and large pack sizes to match a range of research scales.
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- Mi et al. (1993). Asymmetric catalytic alkylation of 4-chlorophenylacetic acid. Tetrahedron: Asymmetry doi:10.1016/s0957-4166(00)82238-7
- MI et al. (1994). ChemInform Abstract: Asymmetric Catalytic Alkylation of 4‐Chlorophenylacetic Acid.. ChemInform doi:10.1002/chin.199402147
- Stuhr et al. (2018). Investigation of the co-metabolic transformation of 4-chlorostyrene into 4-chlorophenylacetic acid in Pseudomonas fluorescens ST. Biotechnology Reports doi:10.1016/j.btre.2018.e00248
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