Allyl Cyanoacetate (TCI C1039, CAS 13361-32-5) is a versatile building block featuring an active methylene group flanked by nitrile and ester functionalities. This arrangement makes it an excellent carbon nucleophile for Knoevenagel condensations, Michael additions, and multicomponent heterocycle synthesis. The allyl ester adds a further handle for palladium-catalyzed deprotection, metathesis, and polymerization chemistry. AMI Scientific offers this reagent in 25 g and 500 g packs; handle it in a fume hood with suitable personal protective equipment.
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