2-Chlorobenzophenone (CAS 5162-03-8) from TCI is a diaryl ketone bearing an ortho-positioned chlorine atom. The carbonyl group readily undergoes reduction, organometallic addition, and condensation to imines or oximes, while the ortho chloride enables intramolecular cyclisation toward fused ring systems. It is a well-known precursor in benzodiazepine chemistry and in ultraviolet-absorbing benzophenone materials. AMI Scientific supplies this reagent in 25 g, 100 g, and 500 g pack sizes for research laboratories.
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- Kurt et al. (2007). Copper(II) and palladium(II) complexes of 2-amino-5-chlorobenzophenone and 2-(2-hydroxybenzylidene)amino-5-chlorobenzophenone-S-methyl-thiosemicarbazones. Transition Metal Chemistry doi:10.1007/s11243-007-0196-4
- Vasco-Mendez et al. (1996). Crystal Structure of 2-Amino-5-chlorobenzophenone. Analytical Sciences doi:10.2116/analsci.12.677
- Javed et al. (2018). 2-Amino-5-chlorobenzophenone. IUCrData doi:10.1107/s241431461801444x
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