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Description
TCI C1421 5-Chlorovaleronitrile (CAS 6280-87-1) is a bifunctional aliphatic building block carrying a terminal nitrile and a terminal chloride. The two groups react under different conditions, allowing sequential transformation into amines, carboxylic acids, or nitrogen heterocycles. It is frequently used as a precursor for piperidine and pyrrolidine ring formation through intramolecular cyclisation. Nitriles are toxic, so handle this reagent in a fume hood with full personal protective equipment.
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