Ceftizoxime TCI C2622

Chemical Identity

CAS No.: 68401-81-0
Formula: C13H13N5O5S2
Molecular weight: 383.40 g/mol
Purity: >98.0%(HPLC)(T)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
SMILES: CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=CCS3)C(=O)O
InChIKey: NNULBSISHYWZJU-LLKWHZGFSA-N
MDL: MDL00072000
PubChem: CID 6533629

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Ceftizoxime is an antibiotic belonging to the second-generation cephalosporin family, widely utilized in laboratory settings for its ability to inhibit bacterial growth. It plays a crucial role in various experimental procedures, particularly in microbiological research and pharmaceutical development. This compound is essential for studying bacterial behavior and testing the efficacy of antimicrobial agents. Its broad-spectrum activity makes it a valuable tool for researchers aiming to understand bacterial resistance patterns and develop new therapeutic strategies.

Ceftizoxime is known for its strong antibacterial activity against gram-negative bacteria, including *Escherichia coli* and *Klebsiella pneumoniae*. Its chemical stability under specific conditions and solubility in organic solvents like ethanol and acetone enhance its usability in chemical reactions and purification processes. Additionally, its resistance to beta-lactamase enzymes ensures effectiveness against bacteria that are resistant to other antibiotics. These properties make Ceftizoxime a preferred choice for laboratory applications requiring reliable and consistent results.

In Indonesian laboratories, Ceftizoxime is extensively used in medical, pharmaceutical, and microbiological research. It is a key component in studies focused on infection control, antibiotic development, and drug efficacy testing. Its reliability and effectiveness have made it a primary choice for researchers working on bacterial resistance and therapeutic innovation. The compound’s versatility supports a wide range of scientific investigations, contributing to advancements in healthcare and scientific knowledge.

Bacterial Sensitivity Testing – Ceftizoxime is used to determine the susceptibility of bacteria to antibiotics, helping in the identification of effective treatments.
Antibiotic Efficacy Evaluation – It is employed to assess the effectiveness of antibiotics against gram-negative bacterial strains in controlled environments.
Infection Control Research – Ceftizoxime supports studies on bacterial resistance and the development of strategies to combat infections in clinical and laboratory settings.
Pharmaceutical Development – It is utilized in the formulation and testing of new antibiotics, ensuring they meet the required standards for potency and safety.
Microbial Culture Studies – Ceftizoxime aids in the growth and analysis of bacterial cultures, providing insights into microbial behavior and interactions.

Brand	TCI
CAS number	68401-81-0
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Antibiotics
Pack sizes	Available in various quantities as per standard laboratory requirements
Physical form	Powder
Storage	Store in a cool, dry place away from direct sunlight

Ceftizoxime should be stored in a cool, dry place, away from direct sunlight and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent contamination and degradation. In laboratory settings, proper personal protective equipment (PPE) such as gloves and safety goggles should be worn when handling the compound. Avoid exposure to incompatible substances and ensure adequate ventilation in the workspace. Regular monitoring of storage conditions is advised to ensure the integrity of the material. Proper handling and storage practices help maintain the effectiveness and safety of Ceftizoxime in laboratory applications.

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