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TCI

CAS 96946-42-8

Cisatracurium Besylate TCI C2940

Cisatracurium Besylate TCI C2940
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Description

TCI C2940 is Cisatracurium Besylate, a benzylisoquinolinium-class compound supplied as a pharmaceutical research reagent intended for experimental laboratory use. The molecule is one of the isomers within the atracurium group and is widely documented in the pharmacological literature as a non-depolarizing neuromuscular blocking agent. In a laboratory setting, this material serves as a reference substance and test compound for receptor pharmacology studies, analytical method development, and pharmaceutical chemistry research that requires an active compound with a clearly defined chemical identity and consistent quality from lot to lot.

The characteristics that make this material important to researchers are the distinctive nature of its stereochemistry and its degradation pathway. As a bis-quaternary ammonium compound, the molecule is strongly polar and carries a permanent charge, so its solubility behaviour and chromatographic separation differ markedly from those of ordinary neutral compounds. The atracurium family of compounds is also known to break down through Hofmann elimination, a process dependent on pH and temperature. That property makes the material a valuable subject for chemical stability studies, degradation kinetics work, and analytical method validation, where a well-characterised degradation route is an advantage rather than a limitation.

In Indonesian laboratories, this reagent is typically used in university pharmacy and pharmaceutical chemistry departments, in research institutes, and in analytical laboratories developing or validating methods for compounds of this class. It is normally handled in small quantities as a reference and test material within controlled experimental work, supporting instructional research, method development, and stability investigations that require a compound whose chemical identity is unambiguous and reproducible across studies.

Laboratory Applications

  • Receptor pharmacology studies — the compound is well documented as a non-depolarizing neuromuscular blocking agent, making it a suitable test article for experimental investigations of receptor behaviour.
  • Analytical method development — its permanent charge and strongly polar character give distinctive chromatographic retention behaviour, providing a demanding and instructive test compound for separation method design.
  • Chemical stability studies — the known Hofmann elimination pathway, which depends on both pH and temperature, allows controlled examination of how storage and solution conditions affect compound integrity.
  • Degradation kinetics research — the defined breakdown route of the atracurium group supports quantitative measurement of degradation rates under varied experimental temperature and pH conditions.
  • Analytical method validation — consistent chemical identity between lots makes the material appropriate as a reference substance when confirming the specificity and reliability of laboratory methods.

Specifications

  • Brand: TCI
  • CAS Number: 96946-42-8
  • Category: Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents (for Experimental Use)
  • Compound class: Benzylisoquinolinium compound; bis-quaternary ammonium structure
  • Pack sizes: available in the pack sizes listed for this catalogue item
  • Storage: store according to the conditions stated on the product label and accompanying documentation

Handling and Storage

Store this reagent in a cool place, protected from heat, light, and moisture, and follow the storage conditions indicated on the product label. Because the compound is susceptible to Hofmann elimination, which is influenced by pH and temperature, avoid unnecessary warming and prepare solutions only as required for immediate experimental use. Keep the material in tightly closed original containers, or in chemically compatible sealed glass containers when transferring, and label all vessels clearly. Handle only in a properly ventilated laboratory using appropriate personal protective equipment, including gloves, safety glasses, and a laboratory coat. This product is for experimental laboratory use and should be managed under normal institutional chemical handling and waste disposal procedures.

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