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Description
TCI D2068 trans-2-Dodecenal is an unsaturated aldehyde built on a twelve-carbon chain, carrying a single carbon–carbon double bond in the trans configuration at the alpha-beta position relative to the aldehyde group. Within the Life Science portfolio it is classified under Biochemicals and Reagents as a lipid, and it is recognised as a naturally occurring aroma component found in several spice plants. In the laboratory it serves as a reference material or standard for aroma analysis, as a test substance in studies of the biological activity of lipids, and as an intermediate in long-chain organic synthesis.
The property that makes this compound a preferred choice is its characteristic conjugated enal structure. Because the carbonyl group is directly connected to the double bond, the molecule presents a dual electrophilic centre, allowing it to undergo conjugate addition with biological nucleophiles such as thiol and amino groups. This reactivity underlies the substantial body of research into the antimicrobial activity and biological interactions of long-chain unsaturated aldehydes. The defined trans configuration is equally important, since double-bond geometry strongly influences both the aroma character and the biological response of the compound.
In Indonesian laboratories this material fits naturally into flavour and fragrance research, food science departments, and academic groups investigating bioactive lipids. As a liquid it is straightforward to pipette and to dispense into small working volumes, which suits the modest reaction and assay scales typical of university and institutional research settings. It is generally handled as a reference or comparison substance alongside chromatographic and spectroscopic work, and is drawn from a single container across a series of experiments to keep results consistent.
Laboratory Applications
Aroma and flavour profiling — the compound serves as a comparison substance or standard, letting analysts confirm the identity of a naturally occurring aroma component detected in plant-derived samples.
Bioactivity screening of lipids — its conjugated enal system reacts with thiol and amino nucleophiles, making it a suitable test substance for studies of antimicrobial and biological interaction mechanisms.
Long-chain organic synthesis — the twelve-carbon backbone with a reactive alpha-beta unsaturated aldehyde terminus functions as an intermediate for building extended aliphatic structures in preparative work.
Conjugate addition chemistry — the dual electrophilic centre created by the carbonyl adjacent to the double bond allows controlled Michael-type additions when studying nucleophile reactivity in model systems.
Stereochemistry and structure–activity studies — the defined trans double-bond geometry provides a reference point for research examining how configuration governs aroma character and biological response.
Specifications
Brand: TCI
CAS Number: 20407-84-5
Category: Life Science > Biochemicals and Reagents > Lipids
Chemical class: long-chain alpha-beta unsaturated aldehyde (conjugated enal), trans configuration
Physical form: liquid
Pack sizes: available in standard TCI catalogue pack sizes; please confirm the required size when ordering
Storage: keep in a closed original container under the conditions indicated on the manufacturer's label
Handling and Storage
Store the container tightly closed in a cool, dark, well-ventilated area, away from heat, ignition sources, and strong oxidising agents, and follow the storage conditions stated on the manufacturer's label. Because the material is a reactive unsaturated aldehyde, keep it in its original glass or manufacturer-supplied container rather than transferring it to unsuitable plastics, and limit prolonged exposure to air. Handle and dispense inside a fume hood using appropriate personal protective equipment, including gloves, safety glasses, and a laboratory coat. Its liquid form makes pipetting straightforward, but transfers should be made carefully to avoid vapour release and skin contact. Close the container immediately after use, label any working aliquots clearly, and dispose of residues and contaminated consumables through the laboratory's designated chemical waste route. Consult the manufacturer's safety data sheet before first use.
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