• 1,5-Diiodopentane (stabilized with Copper chip) (CAS 628-77-3) - TCI D2110 - AMI Scientific
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TCI

CAS 628-77-3

1,5-Diiodopentane (stabilized with Copper chip) TCI D2110

1,5-Diiodopentane (stabilized with Copper chip) TCI D2110
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Rp 3.394.650,00
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TCI D2110 1,5-Diiodopentane (stabilized with Copper chip) is a straight-chain, five-carbon aliphatic compound carrying an iodine atom at each end, supplied with copper chips in the packaging as a stabilizer. The material functions as a bifunctional alkylating reagent, meaning both ends of the molecule can react with nucleophiles, which makes it well suited for linking two functional groups together or for closing a ring. In everyday laboratory practice, compounds of this type serve as standard connectors whenever researchers need to install an aliphatic bridge of a defined and precisely measured chain length.

The property that most often drives the selection of this compound is the high reactivity of its iodide groups. Iodide is an excellent leaving group, so nucleophilic substitution reactions proceed under milder conditions than with the corresponding bromide or chloride analogues. This is a real advantage when other substrates in the reaction mixture are sensitive to heating or to strong bases. On the other hand, aliphatic iodides tend to decompose slowly on exposure to light and air, releasing free iodine in the process; the copper chips added as a stabilizer therefore do a great deal to preserve the quality of the material.

In Indonesian laboratories, a reagent of this kind is typically found in synthetic organic chemistry work at universities, research institutes, and industrial R&D units, where a defined aliphatic linker is needed to join two functional groups or to build a ring system. Because the material is light- and air-sensitive, it is normally kept in a dedicated chemical store and dispensed only in the quantity required for each experiment, with the copper chips left undisturbed in the original container.

  • Bifunctional alkylation of nucleophiles: both terminal iodide positions react readily, allowing a single reagent to alkylate two nucleophilic centres in one controlled synthetic sequence.
  • Ring formation by intramolecular cyclization: the five-carbon backbone with reactive ends at both termini lets chemists close rings of a predictable, defined size.
  • Installation of aliphatic linkers: researchers use it whenever a bridge of precisely measured chain length must connect two functional groups within a larger target molecule.
  • Building-block chemistry for non-heterocyclic scaffolds: as a catalogued building block, it supplies a ready aliphatic fragment without requiring separate in-house preparation of the dihalide.
  • Reactions with sensitive substrates: the excellent iodide leaving group permits substitution under milder conditions, protecting co-reagents that would degrade under heat or strong base.

Brand TCI
CAS number 628-77-3
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes —
Physical form —
Storage keep protected from light and air; retain the copper chips in the original container
  • Product code: D2110
  • Composition note: supplied stabilized with copper chips in the packaging

Store the container tightly closed, protected from light and from prolonged contact with air, in a cool and well-ventilated chemical store away from incompatible materials. Amber or otherwise light-shielded glass containers are appropriate, and the copper chips supplied with the material should be left in place rather than filtered off, since they are there to limit slow decomposition and the release of free iodine. Dispense inside a fume hood using clean, dry glassware, and take the usual laboratory precautions for a reactive alkylating agent: wear gloves, safety glasses, and a lab coat, avoid skin and eye contact and inhalation of vapours, and close the container promptly after use. Discoloration toward brown or violet suggests iodine liberation and should be assessed before the material is used.

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