• 1,1-Dimethylsemicarbazide (CAS 22718-49-6) - TCI D3854 - AMI Scientific
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TCI

CAS 22718-49-6

1,1-Dimethylsemicarbazide TCI D3854

1,1-Dimethylsemicarbazide TCI D3854
Rp 2.598.750,00
Rp 2.598.750,00
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TCI D3854 1,1-Dimethylsemicarbazide is a synthetic chemical from the semicarbazide derivative family, carrying two methyl groups on the terminal nitrogen atom. In the laboratory, this compound serves as a non-heterocyclic building block — a small starting material that contributes a nitrogen-carbonyl framework to be assembled into larger molecules. The combination of a substituted hydrazine group and a urea group within a single molecule makes it an efficient nitrogen atom donor, particularly when researchers want to construct nitrogen-rich rings without having to assemble them from several separate reagents.

The characteristic that makes this material a frequent choice is its directed reactivity. The free amino group condenses readily with aldehydes and ketones to form semicarbazone derivatives, while the adjacent pair of nitrogen atoms provides a cyclization pathway toward triazolinone rings and related systems. The dimethyl substitution at one nitrogen terminus limits the possibility of side reactions while simultaneously directing the regioselectivity of the product, so that synthetic routes become cleaner and more predictable. As a TCI product, this material is prepared under quality control appropriate for reproducible synthetic work.

In Indonesian laboratories, 1,1-Dimethylsemicarbazide is typically used in synthetic organic chemistry research groups at universities and in research institution laboratories working on the preparation of nitrogen-containing heterocyclic compounds. It is generally handled at the bench scale, where small quantities of a reliable building block are more practical than multi-step preparation from separate reagents. Its role is usually as an intermediate within a longer synthetic sequence, supporting method development work and the preparation of target compounds for further characterization.

  • Semicarbazone derivative synthesis — the free amino group condenses readily with aldehydes and ketones, making it a direct route to carbonyl derivatives without additional activating reagents.
  • Triazolinone ring construction — the adjacent nitrogen pair offers a built-in cyclization pathway, allowing nitrogen-rich rings to be closed from a single reagent rather than several.
  • Nitrogen-rich heterocycle preparation — the molecule supplies both hydrazine and urea functionality at once, shortening routes toward heterocyclic frameworks requiring multiple nitrogen atoms.
  • Regioselective synthesis method development — the dimethyl substitution blocks one nitrogen terminus, directing product regiochemistry and giving researchers more predictable outcomes during route optimization studies.
  • Multi-step intermediate preparation — as a small non-heterocyclic building block, it contributes a defined nitrogen-carbonyl fragment that can be elaborated further within longer synthetic sequences.

Brand TCI
CAS number 22718-49-6
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes available in standard laboratory research pack sizes; please confirm the currently available packaging when ordering
Physical form —
Storage store in a tightly closed original container in a cool, dry, well-ventilated area
  • Product Code: D3854

Store 1,1-Dimethylsemicarbazide in its original tightly closed container in a cool, dry, and well-ventilated place, away from direct sunlight, heat sources, and moisture. Keep it separated from strong oxidizing agents and from carbonyl compounds that could react with the free amino group during storage. Handle the material inside a fume hood using appropriate personal protective equipment, including safety goggles, chemical-resistant gloves, and a laboratory coat. Avoid inhaling dust and avoid direct contact with skin and eyes. Close the container promptly after weighing to limit exposure to atmospheric moisture, and always consult the manufacturer's Safety Data Sheet before use and for disposal guidance.

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