2,4-Dimethoxy-1,3,5-triazine TCI D3998

Name: TCI D3998 1898-72-2 2,4-Dimethoxy-1,3,5-triazine
Brand: TCI
SKU: TCI2510D399824452
Price: 2421300.0 IDR
Availability: InStock

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Berat 1g 5g

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Description

TCI D3998 2,4-Dimethoxy-1,3,5-triazine (CAS 1898-72-2) is a six-membered aromatic heterocyclic compound containing three alternating nitrogen atoms in the ring, with two methoxy groups attached at the 2 and 4 positions. As a heterocyclic building block, this compound holds high value in organic synthesis laboratories because the triazine ring serves as an electrophilic platform whose reactivity can be tuned in a stepwise manner. The methoxy groups act as leaving groups that can be displaced by nucleophiles, allowing researchers to install amine, alkoxy, or thiol substituents onto the triazine framework in a controlled fashion.

The characteristic that makes this compound a frequent choice is the electron deficiency of the triazine ring, which permits nucleophilic aromatic substitution without requiring extreme conditions, together with the third ring position that remains available for further functionalization. The difference in reactivity between positions enables sequential substitution strategies, so that asymmetrically substituted triazine products can be designed systematically. The flat, nitrogen-rich triazine ring also contributes hydrogen-bond accepting ability and aromatic stacking interactions, properties that are useful in molecular design work.

In Indonesian laboratories, this building block is typically used in synthetic organic chemistry research groups at universities and research institutes, as well as in industrial R&D units that develop new molecular structures. It is commonly handled at bench scale for exploratory reactions, method development, and the preparation of substituted triazine intermediates that are later carried forward into larger synthetic sequences or characterization studies.

Laboratory Applications

Nucleophilic aromatic substitution studies — the electron-deficient triazine ring undergoes displacement of methoxy groups under moderate conditions, making it a dependable substrate for teaching and probing SNAr reactivity.
Sequential functionalization of triazine scaffolds — differing reactivity between the 2, 4, and 6 positions lets chemists install substituents one at a time toward asymmetrically substituted triazine targets in a planned order.
Preparation of amine-substituted triazine intermediates — methoxy groups serve as leaving groups readily displaced by amine nucleophiles, giving controlled access to aminotriazine structures for downstream synthetic steps.
Molecular design and scaffold exploration — the flat, nitrogen-rich ring offers hydrogen-bond accepting sites and aromatic stacking interactions, valuable when researchers evaluate new core structures during discovery work.
Alkoxy and thiol derivatization chemistry — the compound accepts alkoxide and thiol nucleophiles at the activated ring positions, supporting the systematic construction of diversified triazine libraries in synthesis laboratories.

Specifications

Brand: TCI
CAS Number: 1898-72-2
Chemical Name: 2,4-Dimethoxy-1,3,5-triazine
Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack Sizes: available in standard laboratory research pack sizes as supplied by the manufacturer
Storage: keep in the tightly closed original container under the conditions stated on the manufacturer's label and safety data sheet

Handling and Storage

Store the material in its original tightly closed container in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and incompatible chemicals, following the conditions specified on the manufacturer's label and safety data sheet. Because methoxy-substituted triazines are reactive toward nucleophiles, containers should be kept sealed and protected from moisture, and transfers should be performed promptly to limit exposure to ambient air. Handle in a functioning fume hood using appropriate personal protective equipment, including chemical-resistant gloves, safety glasses, and a laboratory coat. Use clean, dry glassware or compatible plastic containers for weighing and transfer, and avoid generating dust. Label all secondary containers clearly, keep the safety data sheet accessible at the point of use, and dispose of residues and contaminated materials through the laboratory's approved chemical waste procedures.